Cannabinoids and Pain

1. Auflage 2021
ISBN: 978-3-030-69185-1
Verlag: Springer International Publishing

Buch, Englisch, 339 Seiten, Paperback, Format (B × H): 178 mm x 254 mm, Gewicht: 759 g

This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions.

Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain.

Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research.

Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Narouze, Samer N.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Allgemeinmedizin, Familienmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Schmerzmedizin & Schmerztherapie

Inhaltsverzeichnis

History of Cannabis.- Cannabis Regulations.- The demand for medical cannabis education.- Pain physicians and cannabis: attitudes and beliefs.- Cannabis Terminology.- THE ENDOCANNABINOID SYSTEM.- The CB1 Receptors.- The CB2 Receptors.- Endocannabinoids: Anandamide and 2-AG.- Phytocannabinoids:Tetrahydrocannabinol (THC) .- Phytocannabinoids:  Cannabidiol (CBD).- Other Phytocannabinoids.- Cannabinoids Drug interaction.- Dronabinol (Marinol).- Nabilone (Cesamet).- Cannabidiol (Epidiolex).- Nabiximols (Sativex).- Medical Cannabis Strains.- The model of a specialized cannabis clinic.- Barriers for the prescription of cannabis-based medicines .- Practical recommendations for the use of medical cannabis.- Medical Cannabis Dosing and Titration.- Patient safety considerations.- Cannabinoids and Pain: Mechanisms of action .- Cannabinoids and Pain: Clinical Evidence.- Cannabinoids and Cancer Pain.- Cannabinoids as a substitute for opioids: Basic science and Clinical evidence.- Cannabiinoids as a substitute for opioids: Suggested algorithm .- Perioperative management of patients on cannabinoids.- The Colorado Experience.- Product Safety and Quality control.- Cannabis and brain development.- Cannabis and mental health risks.- Cannabis and adolescents.- Cannabis and child development during and after pregnancy.- Cannabis impairment and Adverse events.- Vaping hazards.- Cannabis Use Disorder.- Cannabis withdrawal  .- Future research.

Über Autor(innen)

Samer Narouze, MD, PhD

Northeast Ohio Medical University

Center for Pain Medicine

Western Reserve Hospital

Cuyahoga Falls, OH, USA

Caroline MacCallum, MD FRCPC, BSc Pharm

Clinical Instructor Dept. of Med., Adjunct Professor Faculty Pharm. Sc.

Associate. Member Division of Palliative Care| 

University of British Columbia

Medical Director

Greenleaf Medical Clinic

Vancouver, BC, Canada