Natural Product Biosynthesis by Microorganisms and Plants Part B

Erscheinungsjahr 2012
ISBN: 978-0-12-394291-3
Verlag: William Andrew Publishing

Buch, Englisch, 462 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 750 g

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants.

Zielgruppe

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists

Autoren/Hrsg.

Weitere Mitwirkende

Hopwood, David A.

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie Biochemie
• Naturwissenschaften Chemie Analytische Chemie
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Enzymologie
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

- In vivo production of thiopeptide variants
- Microviridin biosynthesis
- Cyclotide isolation and characterization
- Ribosomally-encoded cyclic peptide toxins from mushrooms
- The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase
- Discovery and biosynthesis of phosphonate and phosphinate natural products
- RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins
- Fe(II)-dependent, uridine-5'-monophosphate a-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides
- Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE
- Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example
- The rare fluorinated natural products and biotechnological prospects for fluorine enzymology
- Enzymatic chlorination and bromination
- Prenyltransferases of the dimethylallyltryptophan synthase superfamily
- Serine carboxypeptidase-like acyltransferases from plants
- 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis
- Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis
- High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer