Applied Cross-Coupling Reactions

2013
ISBN: 978-3-642-44016-8
Verlag: Springer

Buch, Englisch, Band 80, 245 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 3927 g

Reihe: Lecture Notes in Chemistry

“Applied Cross-Coupling Reactions” provides students and teachers of advanced organic chemistry with an overview of the history, mechanisms and applications of cross-coupling reactions. Since the discovery of the transition-metal-catalyzed cross-coupling reactions in 1972, numerous synthetic uses and industrial applications have been developed. The mechanistic studies of the cross-coupling reactions have disclosed that three fundamental reactions: oxidative addition, transmetalation, and reductive elimination, are involved in a catalytic cycle. Cross-coupling reactions have allowed us to produce a variety of compounds for industrial purposes, such as natural products, pharmaceuticals, liquid crystals and conjugate polymers for use in electronic devices. Indeed, the Nobel Prize for Chemistry in 2010 was awarded for work on cross-coupling reactions. In this book, the recent trends in cross-coupling reactions are also introduced from the point of view of synthesis design and catalytic activities of transition-metal catalysts.

Zielgruppe

Research

Autoren/Hrsg.

Nishihara, Yasushi

Fachgebiete

• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Chemie Physikalische Chemie Chemische Reaktionen, Katalyse

Inhaltsverzeichnis

Metal-Catalyzed Cross-Coupling Reactions.- A Historical Overview of Metal-Catalyzed Cross-Coupling Reactions.- Mechanism and Fundamental Reactions.- Applications of Cross-Coupling Reactions.- Natural Product Synthesis.- Pharmaceuticals.- Liquid Crystals.- Conjugated Polymers.- Recent Advances in Cross-Coupling Reactions.- With Aryl Chlorides, Tosylates, and Methylates.- With Alkyl Electrophiles.