Buch, Englisch, 400 Seiten, Format (B × H): 163 mm x 241 mm, Gewicht: 681 g
Buch, Englisch, 400 Seiten, Format (B × H): 163 mm x 241 mm, Gewicht: 681 g
Reihe: Wiley-Interscience Series on Mass Spectrometry
ISBN: 978-1-118-13513-6
Verlag: Wiley
Reviews all the latest basic and clinical research findings
With contributions from leading international experts in the field, this book is dedicated to all facets of uremic toxins research, including low molecular weight solutes, protein-bound solutes, and middle molecules. Moreover, it covers everything from basic mass spectrometry research to the latest clinical findings and practices.
"Uremic Toxins" is divided into three sections: Section One, Uremic Toxins, explores the definition, classification, listing, and mass spectrometric analysis of uremic toxinsSection Two, Selected Uremic Toxins, describes key uremic toxins, explaining chemical structures, metabolism, analytical methods, plasma levels, toxicity, clinical implications, and removal methods. Among the uremic toxins covered are indoxyl sulfate, asymmetric dimethylarginine, PTH, 2-microglobulin, and AGEsSection Three, Therapeutic Removal of Uremic Toxins, describes how uremic toxins can be removed by hemodialysis, peritoneal dialysis, and oral sorbent
All chapters are based on the authors' thorough review of the literature as well as their own personal laboratory and clinical experience. References at the end of each chapter provide a gateway to the literature in the field.
Reviewing all the latest basic and clinical research findings, "Uremic Toxins "will help bench scientists in nephrology advance their own investigations. It will also help clinicians take advantage of the latest tested and proven treatments for the management of chronic kidney disease.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
SECTION 1: UREMIC TOXINS
Chapter 1. Uremic Toxins: An Integrated Overview of Definition and Classification
Richard J. Glassock and Shaul G. Massry
Chapter 2. Classification and a List of Uremic Toxins
Nathalie Neirynck, Rita De Smet, Eva Schepers, Raymond Vanholder, and Griet Glorieux
Chapter 3. Analysis of Uremic Toxins with Mass Spectrometry
Toshimitsu Niwa
SECTION 2: SELECTED UREMIC TOXINS
Chapter 4. Indoxyl Sulfate
Toshimitsu Niwa
Chapter 5. p-Cresyl Sulfate
Anneleen Pletinck, Raymond Vanholder, and Griet Glorieux
Chapter 6. 3-Carboxy-4-methyl-5-propyl-2-furanpropionic Acid
Toshimitsu Niwa
Chapter 7. Phenylacetic Acid
Anna Schulz and Joachim Jankowski
Chapter 8. Homocysteine and Hydrogen Sulfide: Two Opposing Aspects in the Pathobiology of Sulfur Compounds in Chronic Renal Failure
Alessandra F. Perna and Diego Ingrosso
Chapter 9. Guanidino Compounds
Sunny Eloot, Griet Glorieux, Peter Paul De Deyn, and Raymond Vanholder
Chapter 10. Asymmetric Dimethylarginine
Vladimír Teplan and Jaroslav Racek
Chapter 11. Nicotinamide Metabolites
Przemyslaw Rutkowski and Boleslaw Rutkowski
Chapter 12. Dicarbonyls (Glyoxal, Methylglyoxal, and 3-Deoxyglucosone)
Naila Rabbani and Paul J Thornalley
Chapter 13. Glucose Degradation Products in Peritoneal Dialysis
Monika Pischetsrieder and Sabrina Gensberger
Chapter 14. Dinucleoside Polyphosphates
Joachim Jankowski and Vera Jankowski
Chapter 15. Parathyroid Hormone
Shaul G. Massry and Miroslaw Smogorzewski
Chapter 16. ß2-Microglobulin
Suguru Yamamoto, Junichiro James Kazama, Hiroki Maruyama, Ichiei Narita, and Fumitake Gejyo
Chapter 17. Cytokines
Björn Anderstam, Bengt Lindholm, and Peter Stenvinkel
Chapter 18. Free Immunoglobulin Light Chains
Gerald Cohen and Walter H. Hörl
Chapter 19. Advanced Glycation End-Products (AGEs)
Naila Rabbani and Paul J Thornalley
Chapter 20. Oxidized Albumin
Maurizio Bruschi, Giovanni Candiano, Laura Santucci, and Gian Marco Ghiggeri
SECTION 3: THERAPEUTIC REMOVAL OF UREMIC TOXINS
Chapter 21. Therapeutic Removal of Uremic Toxins by Hemodialysis
Tammy L. Sirich, Pavel Aronov, and Timothy W. Meyer
Chapter 22. Therapeutic Removal of Uremic Toxins by Peritoneal Dialysis
Malgorzata Debowska, Elvia García-López, Jacek Waniewski, and Bengt Lindholm
Chapter 23. Therapeutic Removal of Uremic Toxins by Oral Sorbent
Toshimitsu Niwa
Index
