Colloid and Interface Science in Pharmaceutical Research and Development

Erscheinungsjahr 2014
ISBN: 978-0-444-62614-1
Verlag: Elsevier Science

Buch, Englisch, 532 Seiten, Format (B × H): 196 mm x 239 mm, Gewicht: 1293 g

Colloid and Interface Science in Pharmaceutical Research and Development describes the role of colloid and surface chemistry in the pharmaceutical sciences. It gives a detailed account of colloid theory, and explains physicochemical properties of the colloidal-pharmaceutical systems, and the methods for their measurement.

The book starts with fundamentals in Part I, covering fundamental aspects of colloid and interface sciences as applied to pharmaceutical sciences and thus should be suitable for teaching. Parts II and III treat applications and measurements, and they explains the application of these properties and their influence and use for the development of new drugs.

Zielgruppe

<p>Primary Market: Scientists, engineers, and students in the field of pharmaceutical science who want to understand colloid and interface science. This book can be used both for teaching and research.</p> <p>Secondary Market: Scientists, engineers, and students in the field of colloid and interface science who want to understand pharmaceutical science.</p>

Autoren/Hrsg.

Ohshima, Hiroyuki

Makino, Kimiko

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Naturwissenschaften Chemie Physikalische Chemie Kolloidchemie

Inhaltsverzeichnis

Part I Fundamentals

Interaction between drugs

Pharmaceutical suspensions

Response of colloidal drugs to external fields

Aggregation of drugs

Concentrated drug particles

Rheology of colloidal suspensions

Part II Applications of Colloid and Interface Science in Pharmaceutical sciences

Liposomes and micelles

Binding of drugs on liposomes

Drug delivery system

Gold nanoparticles

Drug permeation through biological membranes

EPR effects

Part III Measurements

Zeta potential of colloidal drugs

Atomic force microscope

Surface force apparatus

Über Autor(innen)

Ohshima, Hiroyuki
Hiroyuki Ohshima is a Professor Emeritus at the Tokyo University of Science, Japan, where he has worked since 1985. He received his BS (1968), MS (1970), and PhD (1974) degrees in Physics from the University of Tokyo. He completed his postdoc studies at the University of Melbourne, Australia (1981-1983), the State University of New York at Buffalo, USA (1983-1984), and the University of Utah, USA (1984-1985). He was previously a Professor of Pharmaceutical Sciences at the Tokyo University of Science (1994-2012) before retirement and is now Professor Emeritus and Visiting Professor.

Makino, Kimiko
Kimiko Makino is a Professor of Pharmaceutical Sciences at the Tokyo University of Science, Japan. She is the author or co-author of 1 book and over 120 book chapters and journal publications reflecting her research interests in colloid and interface sciences as well as pharmaceutical science. She spent her post-doc life at University of Utah. Dr. Makino received the B.S. (1979), M.S. (1981), and Ph.D. (1986) degrees in pharmaceutical science from Tokyo University of Science. She currently serves as the head of the Center for Physical Pharmaceutics of Tokyo University of Science. She has just been appointed as new Co-Editor in Chief of Journal of Microencapsulation (Informa Healthcare/Taylor & Francis).