Smart Polymeric Nano-Constructs in Drug Delivery

Concept, Design and Therapeutic Applications
Erscheinungsjahr 2022
ISBN: 978-0-323-91248-8
Verlag: Elsevier Science

Buch, Englisch, 624 Seiten, Format (B × H): 188 mm x 234 mm, Gewicht: 1238 g

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems.

Zielgruppe

Pharmaceutical scientists, post graduate students, clinical researchers, and specialists working in targeted drug delivery; Researchers and advanced students in chemistry and pharmacy and those in the field of polymers and nanotechnology

Autoren/Hrsg.

P Vyas, Suresh

Agrawal, Udita

Sharma, Rajeev

Fachgebiete

• Wirtschaftswissenschaften Wirtschaftssektoren & Branchen Fertigungsindustrie Pharmaindustrie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Introduction to smart polymers and their applications
2. Thermoresponsive polymers: Phase behaviour, drug delivery and biomedical applications
3. pH-sensitive polymeric nanocarriers for enhanced intracellular drug delivery
4. Photo-responsive nanocarriers for delivery of bioactives
5. Magnetically responsive polymer gels and elastomers for drug delivery
6. Bioadhesive and phase-change polymers for drug delivery
7. Block copolymer micelles as long-circulating drug vehicles
8. Polymer-drug conjugates: origins, progress to date and future directions
9. Molecularly imprinted polymers for drug delivery
10. Dendritic polymer macromolecular carriers for drug delivery
11. Hydrogels: from controlled release to pH-responsive drug delivery
12. Stimuli-responsive protein fibres for advanced applications
13. Smart drug delivery systems and its clinical potential
14. Novel biomimetic polymersomes as polymer therapeutics for drug delivery
15. Bioinspired Platform Conjugated systems for Active Drug Delivery
16. Electrically conductive polymers for drug delivery
17. Polymeric nanomedicine: Principles, Properties, and Regulatory Issues
18. Smart drug delivery systems and their clinical potential
19. Polymer-matrix nanocomposites and its potential applications

Über Autor(innen)

Sharma, Rajeev
Rajeev Sharma is an Assistant Professor at the Amity Institute of Pharmacy, Amity University, Madhya Pradesh, Gwalior, India. He earned his B.Pharm, M.Pharm, and Ph.D. in Pharmaceutical Sciences from Dr. H. S. Gour Central University, Sagar, India. Dr. Sharma has approximately 13 years of experience in both teaching and industry. He has served as a Junior Research Fellow under AICTE, an ICMR-SRF, and a CSIR-RA Fellow during his research career, and has worked as an Assistant Professor in academia and as a Senior Formulation Development Scientist in the R&D industry. Dr. Sharma has edited two international and two national books and has authored over 30 publications and 21 book chapters in international reference books. His work focuses on recent concepts in immunology, nanobiotechnology, novel drug delivery systems, and targeted and controlled drug delivery of bioactives for the treatment of diseases such as cancer and diabetes. He is a life member of the Association of Pharmaceutical Teachers of India (APTI). Dr. Sharma's work has been cited approximately 1,200 times, and he has an h-index of 17. The cumulative impact factor of his published papers is around 120, according to SCOPUS. He is currently working on a research project funded by the Madhya Pradesh Council of Science and Technology (MPCST). Dr. Sharma has received several awards for his research, including the Young Research Scholar award and various awards for best oral and poster presentations at national and international conferences. His current research interest is in nanocarrier-based targeted approaches for the effective delivery of bioactives.

P Vyas, Suresh
Dr Vyas has over 36 years of teaching and research experience at postgraduate level. He is a pioneer scientist in the field of nano-biotechnology and immunology. He has over 325 research publications to his credit published in journals of high scientific impact and has authored 18 reference books including Pharmaceutical Biotechnology, Liposomal Therapeutics, Novel Controlled Drug Delivery Systems, Targeted Drug Delivery Systems, Theory and Practices in Novel Drug Delivery Systems. He is a commonwealth postdoctoral fellowship awardee and has worked under fellowship at School of Pharmacy University of London (U.K.). He is a recipient of Best Scientist award by Association of Pharmacy Professionals (APP) 2014 and many other honors. He serves on the editorial board of multiple international scientific publications including International Journal of Pharmaceutics (Elsevier).

Agrawal, Udita
Dr. Agrawal has over 6 years of teaching and research experience at postgraduate level. She served as associate professor at Sagar Institute of Research and Technology Bhopal and Oriental College of Pharmacy Bhopal. She is Gold Medalist in B. Pharm and M. Pharm from Dr. H. S. Gour University and has been awarded with Pharmaceutical Science Alumi Award, Prof. C. S. Chauhan gold medal and Nagarjuna Award from Dr. H. S. Gour University Sagar (MP). She has received various awards in the field of drug delivery for her outstanding innovative research work including M. P Young Scientist Award 2016, Adina Young Scientist Award 2016 in the field of pharmaceutical and medical sciences and many best poster and oral presentation awards. She has more than 40 publications and book chapters in journals of international repute. She is currently working on targeted drug and peptides delivery systems exploiting polymers and nanobiotechnology.