Pancreatic B Cell Biology in Health and Disease

Erscheinungsjahr 2021
ISBN: 978-0-12-823755-7
Verlag: William Andrew Publishing

Buch, Englisch, 414 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 790 g

Pancreatic B Cell Biology in Health and Disease, Volume 360 presents the latest release in this ongoing series on the novel and widely studied physiology of pancreatic cells in homeostasis and under pathogenic conditions. This new volume includes new chapters on a variety of topics, including Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn, Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell, Pancreatic Beta Cell Dysfunction in Monogenic Diabetes, The Role of MiRNAs In Beta Cell Function, Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function, Enteroviral Infections and Pancreatic Beta Cell Dysfunction, and more.

Final sections cover Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes and Pancreatic Beta Cell Biology in Health and Disease.

Zielgruppe

<p>Clinical and basic diabetologists interested in pancreatic ? cell and its central role in the development of different types of diabetes. </p>

Autoren/Hrsg.

Weitere Mitwirkende

Gomez, Izortze Santin

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

1. Pancreatic Beta Cell Dysfunction in Type 1 Diabetes: The Role of Ifn Laura Marroquí 2. Sexual Hormones and Diabetes: The Impact in Pancreatic Beta Cell Marta Garcia-Arévalo 3. Pancreatic Beta Cell Dysfunction in Monogenic Diabetes Mariana Igoillo-Esteve 4. The Role of Mirnas In Beta Cell Function Flora Brozzi 5. Pancreatic Beta Cell: How Environmental Endocrine Disruptors Alter Its Function Sergio Soriano 6. Enteroviral Infections and Pancreatic Beta Cell Dysfunction Anne Op De Beek 7. Long Non-Coding Rna-Regulated Pathways in Pancreatic Beta Cell: Their Role in Diabetes Izortze Santin 8. Pancreatic Beta Cell Biology in Health and Disease Cesar Martín

Über Autor(innen)

Gomez, Izortze Santin
Izortze Santin is assistant professor and researcher in the Department of Biochemistry and Molecular Biology of the University of the Basque Country (Leioa, Spain). She obtained her PhD in Genetics of autoimmune diseases in 2004, and then, she moved to the ULB Center for Diabetes Research (Brussels, Belgium) where she completed her formation in diabetes with functional studies in in vitro models of pancreatic beta cell and in vivo models of type 1 diabetes. Izortze Santin is best known for major experimental and conceptual contributions to the research of pancreatic beta cell dysfunction in type 1 diabetes. Indeed, her work has highlighted the implication of type 1 diabetes candidate genes in the regulation of several pathways related to pancreatic beta cell inflammation and death.
Currently her main research line aims to characterize how T1D genes (coding and non-coding) and viral infections interact to trigger the autoimmune destruction of pancreatic beta cells in type 1 diabetes. To this aim, she has several ongoing funded projects related to type 1 diabetes pathogenesis, in which the study of pancreatic beta cell acquired a central role.