Parimelazhagan Pharmacological Assays of Plant-Based Natural Products

1. Auflage 2016
ISBN: 978-3-319-26811-8
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 71, 188 Seiten, eBook

Reihe: Progress in Drug Research

This volume provides information on how to select and screen plants for their medicinal properties. It describes phytopharmacological techniques for extracting and qualitatively and quantitatively analyzing a plant’s phytochemicals. After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc. Compound identification and purification techniques include, among others, TLC and column chromatography, as well as molecular docking with specific proteins.

Zielgruppe

Research

Autoren/Hrsg.

Parimelazhagan, Thangaraj

Inhaltsverzeichnis

1. Extraction of plant material.- 2. Critical aspects of purification and impurities in natural product extracts. 3.  In vitro antioxidant assays.- 4.  In vivo  antioxidant assays.- 5. Quantification assays.- 6. Anti-nutritional factors.- 7. Anti-inflammatory activity.- 8. Antipyretic activity.- 9. Inflammation bowel disease.- 10. Anti-arthritic activity.- 11. Evaluation of analgesic potential.- 12. Anti-diarrhoeal activity.- 13. Anti-ulcer activity.- 14. In vitr o anti-diabetic activity.- 15.  In vivo anti-diabetic activity.- 16. Hepatoprotective property.- 17. Antitumor activity.- 18.  In vivo  wound healing studies.- 19. Determination of cytotoxicity.- 20. Evaluation of bioavailability.- 21. Molecular identification by DNA barcoding.- 22. Molecular docking of bioactive compounds against BRCA and COX proteins.

Über Autor(innen)

Parimelazhagan Thangaraj is a Professor in the Department of Botany, Bharathiar University, Coimbatore – 641 046, India. His field of specialization is Bioprospecting of Medicinal Plants. He is currently engaged in compilation and documentation on available knowledge on valuable plant resources to prove their utility scientifically through detailed phytochemical, biological and pharmacological investigations.