Pharmacology of 5-HT6 receptors, Part II

Erscheinungsjahr 2011
ISBN: 978-0-12-385902-0
Verlag: William Andrew Publishing

Buch, Englisch, 242 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 510 g

The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

Zielgruppe

Neuroscientists, neurologists, psychologists, psychiatrists, pharmacologists

Autoren/Hrsg.

Weitere Mitwirkende

Borsini, Franco

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Neuropharmakologie, Psychopharmakologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

- The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry Lee A Dawson

- 5-HT6 receptor memory and amnesia. Behavioral Pharmacology: Learning and Memory Processes Alfredo Meneses, Pérez-García G, Tellez R, Ponce-Lopez T and C Castillo

- Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties Anna Wesolowska, Magdalena Jastrzebska-Wiesek

- The 5-Ht6 Receptor as a Target for Developing Novel Anti Obesity Drugs David Heal, Jane Gosden, and Sharon Smith

- Behavioral and neurochemical pharmacology of 5-HT6 receptors related to reward and reinforcement. Gaetano Di Chiara, Valentina Valentini and Sandro Fenu

- 5-HT6 Receptor Ligands and their Antipsychotic Potential Jørn Arnt and Christina Kurre Olsen

- 5-HT6 Receptor Ligands as Antidementia Drugs Ellen Siobhan Mitchell

Über Autor(innen)

Borsini, Franco
Franco Borsini, Head, Central & Peripheral Nervous System and General Pharmacology Area - R&D Department, sigma-tau SpA, Pomezia (Rome), Italy