Neuropathology of Drug Addictions and Substance Misuse, Volume 3

General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions
Erscheinungsjahr 2016
ISBN: 978-0-12-800634-4
Verlag: Elsevier Science

Buch, Englisch, 1106 Seiten, Format (B × H): 221 mm x 282 mm, Gewicht: 2449 g

Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions.

Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances.

Autoren/Hrsg.

Preedy, Victor R

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pathologie, Cytopathologie, Histopathologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie

Inhaltsverzeichnis

Part I. Principles of Addictions, Overviews, Detailed Processes and Mechanisms

Section A. General Aspects

Chapter 1. Drugs and the Human Envirome

Chapter 2. Psychoactive Plants Used during Religious Rituals

Chapter 3. Substance Use Disorders and Comorbid Mental Illness: A Focus on Epidemiological Data Regarding Mood and Anxiety Disorders

Chapter 4. Mephedrone and Mephedrone-Based Cocktails: Market, Analysis, Mechanisms of Action, and Toxicity

Chapter 5. Substance-Induced Psychosis: Conceptual and Diagnostic Challenges in Clinical Practice

Chapter 6. Sleep and Drug Addiction

Section B. Molecular and Cellular Aspects

Chapter 7. Hypothalamic and Midbrain Cells, Tyrosine Hydroxylase, and Implications for Drug Addiction

Chapter 8. Oxytocin: Providing New Avenues for Treating and Understanding Problematic Drug Use

Chapter 9. Role of D2-like Heteroreceptor Complexes in the Effects of Cocaine, Morphine, and Hallucinogens

Chapter 10. Glutamate Receptors and Drug Addiction

Chapter 11. Effect of Interacting Nonsteroidal Anti-Inflammatory Agents (NSAIDs) and Opioids on Mood: Pharmacodynamic Considerations in Misuse and Abuse

Chapter 12. A Mini-Review on Different Commonly Used Abusive Drugs and the Interactions of These Drugs and Chinese Herbs

Chapter 13. Interaction of Drugs of Addiction with DNA

Chapter 14. Drugs of Abuse and DNA Methylation in the Brain: Ethanol, Cocaine, Amphetamine-Methamphetamine, Heroin, Antidepressants, and Antipsychotics

Chapter 15. Orexin/Hypocretin System and Drug Addiction

Chapter 16. Reverse Translational Implications of Genome-Wide Association Studies for Addiction Genetics

Chapter 17. Polymorphisms in the Delta Opioid Receptor Gene (OPRD1) and Drug Addiction: Candidate Genes, Transgenic Mouse Models, and Genome-Wide Association Studies

Über Autor(innen)

Preedy, Victor R
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRSC, FRCPath graduated with an Honours Degree in Biology and Physiology with Pharmacology. After gaining his University of London PhD, he received his Membership of the Royal College of Pathologists. He was later awarded his second doctorate (DSc), for his contribution to protein metabolism in health and disease. He is Professor of Clinical Biochemistry (Hon) at King's College Hospital and Emeritus Professor of Nutritional Biochemistry at King's College London. He has Honorary Professorships at the University of Hull, and the University of Suffolk. Professor Preedy was the Founding Director and then long-term Director of the Genomics Centre at King's College London from 2006 to 2020. Professor Preedy has been awarded fellowships of the Royal Society of Biology, the Royal College of Pathologists, the Royal Society for the Promotion of Health, the Royal Institute of Public Health, the Royal Society for Public Health, the Royal Society of Chemistry and the Royal Society of Medicine. He carried out research when attached to the National Heart Hospital (part of Imperial College London), The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with international research groups in Finland, Japan, Australia, USA, and Germany. To his credit, Professor Preedy has published over 750 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and edited books.