Rawlins | Therapeutics, Evidence and Decision-Making | Buch | 978-1-85315-947-3 | sack.de

Buch, Englisch, 256 Seiten, Format (B × H): 156 mm x 233 mm, Gewicht: 423 g

Rawlins

Therapeutics, Evidence and Decision-Making

The Basis for Decisions About the Use of Therapeutic Interventions
1. Auflage 2011
ISBN: 978-1-85315-947-3
Verlag: Taylor & Francis Ltd

The Basis for Decisions About the Use of Therapeutic Interventions

Buch, Englisch, 256 Seiten, Format (B × H): 156 mm x 233 mm, Gewicht: 423 g

ISBN: 978-1-85315-947-3
Verlag: Taylor & Francis Ltd


This book is intended to help decision-makers use, assess and appraise the evidence that underpins decisions about the use of therapeutic interventions. It will inform decision-makers about the nature of evidence, the strengths and weaknesses of the available approaches, and how these can be most effectively distilled for the purpose of reaching reliable conclusions. It aims to encourage decision-makers to base their judgements about the use of therapeutic interventions on an informed appraisal of the totality of the evidence base. Is it reliable? Is it generalisable beyond the context of the environment in which the primary research has been conducted? Do the intervention's benefits outweigh its harms? Is it cost effective as well as clinically effective? Is it, indeed, fit-for-purpose? Ultimately, good judgement is at the heart of decision-making in therapeutics.

An invaluable text for all physicians, pharmacists, nurses, health commissioners and purchasers and indeed anyone having to make decisions concerning evidence-based therapeutics.

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Zielgruppe


Professional Reference

Weitere Infos & Material


Introduction: The nature of evidence. Probability. Clinical endpoints of benefits and harms. Statistical expressions of benefit and harm. Bias and confounding. Systematic reviews. Randomized controlled trials:. General principles. Stopping rules. Analysis of subgroups. Safety. Generalizability. Observational studies: General overview. Historical controlled trials. Concurrent cohort studies. Case-control designs. Databases. Case reports. Qualitative research: Approaches and methods. Uses in the evaluation of therapeutic interventions. Economic evaluation: General principles. Cost-effectiveness, cost-utility and cost-minimization analyses. Cost-consequences analysis. Decision-making:. For individuals. For populations.


"Professor Sir Michael Rawlins MD FRCP(Lond) FRCP(Edin) FFPM FMedSci, National Institute for Clinical Excellence, London, UK

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