Sakamoto / Rubin Modulation of Protein Stability in Cancer Therapy
1. Auflage 2009
ISBN: 978-0-387-69147-3
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 165 Seiten, eBook
ISBN: 978-0-387-69147-3
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark
This comprehensive monograph on the role of protein modulation in cancer therapeutics focuses on targeting molecules that regulate protein stability in a variety of tumors. Topics covered include ubiquitin ligases, deubiquitinating enzymes, and the proteasome.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Ubiquitin Ligases and Cancer.- The 26S Proteasome as a Therapeutic Target in Cancer: Beyond Protease Inhibitors?.- Targeting HAUSP: Killing Two Birds with One Stone.- Modulation of Protein Stability: Targeting the VHL Pathway.- Interrelationship of the Fanconi Anemia/BRCA Pathway.- Targeting the Sumoylation Pathway.- Proteasome Inhibitors.- Targeting Deubiquitinating Enzymes.- Proteolysis Targeting Chimeric Molecules.