Speicher / Antonarakis / Motulsky Vogel and Motulsky's Human Genetics

Problems and Approaches
4th Auflage 2010
ISBN: 978-3-540-37654-5
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 1006 Seiten, eBook

The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour.
For graduates and those already working in medical genetics.

Zielgruppe

Research

Autoren/Hrsg.

Speicher, Michael

Antonarakis, Stylianos E.

Motulsky, Arno G.

Inhaltsverzeichnis

Introduction History of Human Genetics Human Genome Sequence and Variation Chromosomes From Genes to Genomics to Proteomics Formal Genetics of Humans: Modes of Inheritance Linkage Analysis for Monogenic Traits Oligogenic Disease Formal Genetics of Humans: Multifactorial Inheritance and Common Diseases Lessons from the Genome-Wide Studies for Complex Multifactorial Disorders and Traits Epigenetics Human Gene Mutation: Mechanisms and Consequences Human Hemoglobin Human Genetics of Infectious Diseases Gene Action: Developmental Genetics Cancer Genetics The Role of the Epigenome in Human Cancers Population Genetic Principles and Human Populations Consanguinity, Genetic Drift, and Genetic Diseases in Populations with Reduced Numbers of Founders Human Evolution Comparative Genomics Genetics and Genomics of Human Population Structure Genetic Epidemiology Pharmacogenetics Behavioral Genetics The Genetics of Personality Mental Retardation and Intellectual Disability Genetic Factors in Alzheimer Disease and Dementia Genetics of Autism The Genetics of Alcoholism and Other Addictive Disorders Behavioral Aspects of Chromosomal Variants Genetics of Schizophrenia and Bipolar Affective Disorder Model Organisms for Human Disorders Mouse as a Model for Human Disease Caenorhabditis elegans, A Simple Worm: Bridging the Gap Between Traditional And Systems-Level Biology Drosophila as a Model for Human Disease Human Genetics and the Canine System Fish as a Model for Human Disease Genetic Counseling and Prenatal Diagnosis Gene Therapy Cloning in Research and Treatment of Human Genetic Disease Genetic Medicine and Global Health Genetic Databases Databases and Genome Browsers EnsemblGenome Browser Databases in Human and Medical Genetics Subject Index.