Immune Mechanisms of Pain and Analgesia

2003
ISBN: 978-0-306-47692-1
Verlag: Springer US

Buch, Englisch, Band 521, 163 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1240 g

Reihe: Advances in Experimental Medicine and Biology

Immune Mechanisms of Pain and Analgesia is the first volume to discuss a new concept of immune-neural interplays leading to pain or analgesia. It argues the classical view that pain and its control are restricted to the nervous system, offering a comprehensive overview of the emerging area of immune mechanisms in pain and its control. It challenges the traditional view that pain sensation or suppression is attributed exclusively to the nervous system and presents a critical analysis of this new concept. The book is written by an internationally recognized group of researchers and discusses complex and controversial issues such as cytokines and their pain-exacerbating but also analgesic effects, the production of opioids by immune cells, peripheral analgesic and anti-inflammatory actions of opioids, immunomodulatory effects of opiates, and immunosuppressive effects of pain.

Zielgruppe

Research

Autoren/Hrsg.

Stein, Christoph

Machelska, Halina

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Anästhesiologie
• Naturwissenschaften Biowissenschaften Biowissenschaften Evolutionsbiologie
• Sozialwissenschaften Psychologie Allgemeine Psychologie Biologische Psychologie, Neuropsychologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Veterinärmedizin Veterinärmedizin
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete AINS Schmerzmedizin & Schmerztherapie

Inhaltsverzeichnis

Opioid receptors on immune cells Effects of opioids on the immune system: Experimental evidence for immunomodulatory effects of opioids Clinical relevance of immunomodulatory effects of opiates Opioid peptides in immune cells Opioid receptors on peripheral sensory neurons: Electrophysiology Opioid receptors on peripheral sensory neurons: Anatomical localization and analgesia Immune-suppressive effects of pain Opioids, immune system and pain in invertebrates Cytokines and centrally mediated pain Cytokines and peripherally mediated pain Cytokines and peripheral analgesia Functional evidence of pain control by the immune system Morphological correlates of immune-mediated peripheral opioid analgesia Anti-inflammatory effects of opioids