E-Book, Englisch, 184 Seiten, eBook
St.George-Hyslop / Mobley / Christen Intracellular Traffic and Neurodegenerative Disorders
1. Auflage 2009
ISBN: 978-3-540-87941-1
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 184 Seiten, eBook
Reihe: Research and Perspectives in Alzheimer's Disease
ISBN: 978-3-540-87941-1
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark
Many adult onset neurodegenerative diseases arise from the accumulation of misfolded peptides. This book examines the role sub-cellular trafficking pathways play in the pathological accumulation of these misfolded proteins and in attempts to clear them.
Zielgruppe
Research
Autoren/Hrsg.
Weitere Infos & Material
Amyloid Precursor Protein Sorting and Processing: Transmitters, Hormones, and Protein Phosphorylation Mechanisms.- Intramembrane Proteolysis by ?-Secretase and Signal Peptide Peptidases.- Axonal Transport and Neurodegenerative Disease.- Simple Cellular Solutions to Complex Problems.- Tau and Intracellular Transport in Neurons.- Signaling Between Synapse and Nucleus During Synaptic Plasticity.- Axonal Transport of Neurotrophic Signals: An Achilles' Heel for Neurodegeneration?.- Membrane Trafficking and Targeting in Alzheimer's Disease.- Huntington's Disease: Function and Dysfunction of Huntingtin in Axonal Transport.- The Role of Retromer in Neurodegenerative Disease.- Regulation of Endocytic Trafficking of Receptors and Transporters by Ubiquitination: Possible Role in Neurodegenerative Disease.- The Sortilin-Related Receptor SORL1 is Functionally and Genetically Associated with Alzheimer's Disease.- Regulation of Transport and Processing of Amyloid Precursor Protein by the Sorting Receptor SORLA.
