Buch, Englisch, 472 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 900 g
Bringing Together Experiments and Computing
Buch, Englisch, 472 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 900 g
ISBN: 978-0-12-398312-1
Verlag: Academic Press
Focuses on the recent success in structural and mechanistic enzymology. Has its main emphasis on explaining the enzyme phenomena by using both the experimental and computational approaches. Demonstrates how the application of a variety of experimental techniques and modeling methods helps further the understanding of enzyme dynamics, mechanism, inhibition, and drug design.
Zielgruppe
Biochemists, biophysicists, cell biologists, protein chemists, structural geneticists, and structural biologists
Fachgebiete
- Naturwissenschaften Biowissenschaften Proteinforschung
- Naturwissenschaften Biowissenschaften Enzymologie
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
- Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
- Naturwissenschaften Biowissenschaften Zellbiologie
- Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
- Naturwissenschaften Physik Angewandte Physik Biophysik
Weitere Infos & Material
Structural and Computational Enzymology: Bringing Experiments and Computations Together Tatyana Karabencheva and Christo Christov Structural and Functional Analysis of Proteins by High-Speed Atomic Force Microscopy Arivazhagan Rajendran, Masayuki Endo and Hiroshi Sugiyama Reaction Intermediates Discovered in Crystal Structures of Enzymes Irene T. Weber, Johnson Agniswamy, Guoxing Fu, Chen-Hsiang Shen and Robert W. Harrison Structural, Functional and Mutagenesis Studies of UDP-Glycosyltransferases Vatsala Malik and Gary W Black Vipoxin and its Components: Structure - Function Relationship S. D. Petrova, V. N. Atanasov and K. Balashev Experimental and Theoretical Studies of Enzyme-Catalyzed Hydrogen Transfer Reactions Zhen Wang, Daniel Roston and Amnon Kohen Protein Flexibility and Enzymatic Catalysis M. Kokkinidis, N. M. Glykos and V. E. Fadouloglou Molecular Modeling of Inhibitors of Human DNA Methyltransferase with a Crystal Structure: Discovery of a Novel DNMT1 Inhibitor Jakyung Yoo, Joo Hee Kim, Keith D. Robertson and José L. Medina-Franco In Silico Strategies Towards Enzyme Function and Dynamics Sílvia G. Estácio Dynamic Simulations as a Complement to Experimental Studies of Enzyme Mechanisms Andrew Christofferon, Lifeng Zhao and Qiang Pei The Increasing Role of QM/MM in Drug Discovery Alessio Lodola and Marco De Vivo Probing Allostery and Binding Cooperativity of the Catalytic Subunit of Protein Kinase A by NMR Spectroscopy and Molecular Dynamics Simulations Larry R. Masterson, Alessandro Cembran, Lei Shi and Gianluigi Veglia Using a Combination of Computational and Experimental Techniques to Understand the Molecular Basis for Protein Allostery Wanting Jiao and Emily J. Parker