Encyclopedia of Pharmaceutical Science and Technology, Six Volume Set (Print)

4. Auflage 2013
ISBN: 978-1-84184-819-8
Verlag: Taylor & Francis Ltd

Buch, Englisch, 4296 Seiten, Format (B × H): 348 mm x 273 mm, Gewicht: 12300 g

Pharmaceutical science deals with the whole spectrum of drug development from start to finish. There are many different facets to the pharmaceutical industry, from initial research to the finished product, including the equipment used, trials performed, and regulations that must be followed. Presenting an overview of all of these different aspects, the Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition is a must-have reference guide for all laboratories and libraries in the pharmaceutical field. Bringing together leaders from every specialty related to pharmaceutical science and technology, this is the single-source reference at the forefront of pharmaceutical R&D.

The strength of this work is not only its breadth but also the caliber of contributing writers, all experts in their field, writing on all aspects of pharmaceutical science and technology. The fourth edition offers 29 new chapters ranging from biomarkers, computational chemistry, and contamination control to high-throughput screening, orally disintegrating tablets, and quality by design. The encyclopedia details best practices of equipment used, methods for manufacturing, options for packaging, and routes for drug delivery. The volumes also provide a thorough understanding of the choices behind each method. In addition, the regulations, safety aspects, patent guidance, and methods of analysis are presented.

Key Areas Covered:

- Analytics

- Biomarkers

- Dosage forms

- Drug delivery

- Formulation

- Informatics

- Manufacturing

- Packaging

- Processing

- Regulatory affairs

- Systems validation

This is an authoritative reference source for those practicing in any area of pharmaceutical science and technology, enabling the pharmaceutical specialist and novice alike to keep abreast of developments in this constantly evolving and highly competitive field.

Zielgruppe

Professional

Autoren/Hrsg.

Swarbrick, James

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Wirtschaftswissenschaften Wirtschaftssektoren & Branchen Fertigungsindustrie Pharmaindustrie

Inhaltsverzeichnis

New Chapter Topics: Automated Dissolution Testing. Biomarkers in Drug Discovery and Development. Computational Chemistry. Contamination Control: Cleanrooms and Clean Air Devices. Control of genotoxic impurities in pharmaceutical products. Crystal Form Analysis of Active Pharmaceutical Ingredients (APIs). Drug Delivery using Electrophoresis. Drug Delivery: Inner Ear. Drug Transporters in ADME. Evolutionary Computing and Formulation Optimization. Freeze Drying of Biologicals. Good Publication Practice. High-Throughput Screening (HTS) in Drug Discovery. Impurity Identification in Pharmaceuticals. Injection Molding and its Drug Delivery Applications. Microcalorimetry in Pharmaceutical Development. Multivariate Statistical Analysis. Nano-Needle Systems for Vaccine Delivery. Oral Lipid-Based Formulations. Orally Disintegrating Tablets. Parenteral Formulation: Local Injection Site Reaction and Muscle Tolerance. Particle Shape Analysis. Proteins and Peptides: Physical and Chemical Stability. Quality by Design (QbD) and Analytical Method Development. Quality Target Product Profile (QTPP) for Pharmaceutical Packaging and Delivery Systems. Quality by Design (QbD) in Freeze Drying. Scale-Up of Solid Dispersions. Single-Use Processing in the Pharmaceutical Industry. Statistical Outliers: Methods and Applications.

Über Autor(innen)

James Swarbrick, D.Sc., Ph.D., is the president of PharmaceuTech, Inc., Pinehurst, North Carolina, USA. He has served in a number of industrial and academic positions, including director of product development at Sterling-Winthrop Research Institute, Rensselaer, New York, and vice president for research and development and vice president for scientific affairs at AAIPharma, Wilmington, North Carolina, USA. Prior to joining AAIPharma, he was a professor and chairman of the Division of Pharmaceutics at the University of North Carolina at Chapel Hill School of Pharmacy.

Dr. Swarbrick is a Fellow of the American Association of Pharmaceutical Sciences, the Royal Society of Chemistry, and the Royal Pharmaceutical Society of Great Britain. He has also served as a member and chairman of the FDA’s Generic Drugs Advisory Committee, as chairman of the PhRMA Foundation’s Pharmaceutics Advisory Committee, as well as a member of the PhRMA Foundation’s Scientific Advisory Committee.