Targeted Protein Degradation

Erscheinungsjahr 2023
ISBN: 978-0-323-99200-8
Verlag: William Andrew Publishing

Buch, Englisch, 412 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Targeted Protein Degradation, Volume 680 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of timely topics, with each. Each written by an international board of authors.

Zielgruppe

<p>Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists</p>

Autoren/Hrsg.

Weitere Mitwirkende

Burslem, George

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Alessio Ciulli
2. Mikihiko Naito
3. Philip Chamberlain
4. Danette Daniels, Nidhi Nath and Ellen Crummy
5. Gopal Sapkota
6. Joseph Salvino
7. Lyn H. Jones
8. Stuart H. Orkin, Behnam Nabet and Stuti Mehta
9. Ryan Potts and Robert Guenette
10. Jin Wang
11. Christopher Parker
12. Martin Duplessis
13. Lyn H. Jones
14. Shaomeng Wang
15. Alex Deiters
16. George Burslem

Über Autor(innen)

Burslem, George
George M. Burslem is currently an Assistant Professor for Biochemistry and Biophysics at the Perelman School of Medicine Department of Biochemistry and Biophysics and Department of Cancer Biology, University of Pennsylvania. He was previously a Postdoctoral Fellow at Yale University. He completed his PhD. in the University of Leeds, and his MSci in the University of Bristol Prof. Burslem's lab is interested in developing chemical tools to understand and modulate lysine post-translational modifications, specifically acetylation and ubiquitination. His laboratory is particularly interested in novel pharmacological approaches to modulate post-translational modifications which regulate gene expression and protein stability, employing a multidisciplinary approach including synthetic chemistry, biochemistry, biophysics and cell biology to probe biological systems in cancer biology.