Targeting Signaling Pathways in Solid Tumors Part C

Erscheinungsjahr 2024
ISBN: 978-0-443-23550-4
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Targeting Signaling Pathways in Solid Tumors, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.

Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

Autoren/Hrsg.

Weitere Mitwirkende

Mukherjee, Sumit

Chatterjee, Kaushiki

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

1. Multifaceted perspectives of detecting and targeting solid tumors
Anjan Dasgupta and Abhishek Bhattacharya
2. Tumor microenvironment induced switch to mitochondrial metabolism promotes suppressive functions in immune cells.
Vandana Anang, Sanjay Pandey and Michelle Schumaker
3. DNA damage response (DDR) and neoantigens: A favorable target for triple negative breast cancer (TNBC) immunotherapy and vaccine development
Nityanand Srivastava
4. Role of Interferon Dependent and Independent Signaling pathways: Implications in Cancer
Sheila Spada and Dr Anirban Ganguly
5. Immunological Landscape of Solid Cancer: Interplay Between Tumor and Immune System
Nitin Amdare
6. Targeting mTOR signaling in solid tumors
Vipin Rawat, SOUNAK Ghosh Roy and Subhajit Chatterjee
7. Unraveling the Molecular Basis of PARP Inhibitor Resistance in Prostate Cancer with Homologous Recombination Repair Deficiency
Goutam Chakraborty

Über Autor(innen)

Chatterjee, Kaushiki
As a skilled scientist with expertise in cancer biology, stem cell biology, and epigenetics, I am deeply passionate about advancing scientific knowledge. In my current postdoctoral role, I investigate the role of disease-relevant histone modifiers in shaping the epigenetic landscape of stem cells. My active involvement in multiple projects demonstrates my commitment to collaboration and leveraging collective knowledge to achieve impactful results. I have a track record of mentoring students and actively encouraging diversity in STEM, especially among women pursuing research careers. In my doctoral research, I contributed to understanding the anti-tumor potential of plant polyphenols in cervical cancer. I have published several research and review articles in cancer biology and stem cell epigenetics Through my multifaceted contributions over the course of over 10 years, I aim to inspire the next generation of scientists while leaving a lasting impact on scientific endeavors. Edit

Mukherjee, Sumit
I am a dynamic scientist with broad knowledge and research experience in cancer biology and cancer immunology. I am a highly skilled researcher with exceptional leadership and team-building capabilities. I have 10+ years of cancer research experience in academia as PhD student and Postdoctoral researcher. I have a track record of presenting and publishing scientific data in a timely and organized fashion as attested by my publication record of 12 published research articles with 6 as first-author. I am also a subject matter expert in preclinical cancer immunology as evidenced by my authored review articles with being co-corresponding author for one such review article. I have frequently peer-reviewed multiple articles for publication as peer-reviewer and guest editor. My Postdoctoral work focused on a novel immunosuppressive/protumor cancer cell expressing enzyme ART1's discovery and further developing it as a therapeutic target in lung cancers and melanoma tumors utilizing murine in vivo models and patient samples. My doctoral research specialized in natural product-mediated (like curcumin) therapeutic intervention of cancers by modulating cancer cell signaling and cancer micro-environment immune system. My doctoral research also involved studying the mechanistic underpinning of cancer cell signaling & tumor microenvironment immunology for therapeutic targeting of brain tumors and cervical cancer models.