E-Book, Englisch, 1200 Seiten
Tarloff / Rodriguez / Lash Toxicology of the Kidney, Third Edition
3. Auflage 2004
ISBN: 978-1-134-53652-8
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
E-Book, Englisch, 1200 Seiten
Reihe: Target Organ Toxicology Series
ISBN: 978-1-134-53652-8
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
The kidney plays a vital role in certain endocrine functions. Abnormalities caused by toxic chemicals or other interventions can have profound effects on these functions and consequently, on total functions. Toxicology of the Kidney, Third Edition is updated to reflect the latest research in this field and focuses on the correlation between anatomy, biochemistry, and physiology of the kidney.
The text explains how these factors are related to concepts of clinical nephrotoxicity and renal failure in humans, and how animal models can be used to understand the mechanisms of human renal disease. In addition to updating many of the key elements of previous editions, such as in vitro models for studying renal function and toxicity and classic nephrotoxicants, it also incorporates cutting edge information on newly emerging areas of renal research. These include mechanisms of cell injury, signaling pathways, biomarkers of renal disease and the interface between basic renal science and clinical outcomes.
This book includes current reviews of unpublished and recently published information which allows it to serve as a concise compendium of many key topics that will continue to play a central role in our understanding and treatment of nephrotoxicity for decades to come.
Zielgruppe
Occupational physicians and nurses, toxicologists, industrial hygienists, public health professionals, environmental chemists, environmental health and safety professionals
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
BASIC PRINCIPLES
Anatomy and Physiology, J.M. Sands and J. Verlander
Molecular and Cell Biology of Diseased Kidney, L.H. Lash and J.B. Tarloff
Functional Assessment of the Kidney, L.B, Kinter and S.G. Emiegh
In Vitro Techniques in Screening and Mechanistic Studies: Organ Perfusion, Slices, Nephron Components, D.S. Kilpatrick and A.J. Gandolfi
In Vitro Techniques in Screening and Mechanistic Studies: Cell Culture, Cell-free Systems, Molecular/Cell Biology, S.M. Ford
MECHANISMS OF NEPHROTOXICITY
Role of Xenobiotic Metabolism, G.O. Rankin and M.A. Valentovie
Mechanisms of Renal Cell Death, J.F. Harriman and R.G. Schnellmann
Signal Transduction in Renal Cell Repair and Regeneration, B. van de Water and M. de Graauw
Models of Chemically Induced Renal Carcinogenesis, T.J. Monks and S. Lau
The Role of Endocytosis in Nephrotoxicity, D.P. Sundin and B.A. Molitoris
The Role of Cellular Energetics in Nephrotoxicity, L.H. Lash
Adhesion Molecules in Renal Physiology and Pathology, A.R. Parrish
Oxidant Mechanisms in Toxic Acute Renal Failure, A.G. Basnakian, G.P. Kaushal, N. Ueda, and S.V. Shah
Vasoactive and Inflammatory Substances, G. Remuzzi
CLINICAL NEPHROTOXICITY AND SPECIFIC CLASSES OF NEPHROTOXICANTS
Renal Syndromes Due to Drugs and Chemicals: Clinical Expression of Nephrotoxity, M.E. De Broe
Antibiotic Nephrotoxicity, P.M. Tulkens
Nephrotoxicity of Cyclosporine, Tacrolimus, and Other Immunosuppressive Immunotherapeutic Agents, L.C. Racusen
Cisplatin-Induced Nephrotoxicity, R. Benegio and W. Lieberthal
The Pathogenesis and Prevention of Radiocontrast-Induced Renal Dysfunction, N. Kaperonis, M. Krause, and G.L. Bakris
Analgesics: Acute and Chronic Effects, J.B. Tarloff
Myocotoxins Affecting the Kidney, E. O'Brien and D.R. Dietrich
Heavy Metals, R.K. Zalups and G.L. Diamond
Chemical-Induced Nephrotoxicity Mediated by Glutathione S-Conjugate Formation, W. Dekant
RISK/SAFETY ASSESSMENT
The Role of Epidemiology in Human Nephrotoxicity, M.R.E. McCredie and J.H. Steward
Age, Sex, and Species Differences in Nephrotoxic Response, R.S. Sellers
Risk Assessment Nephrotoxic Metals, G.L. Diamond
Risk Assessment for Selected Therapeutics, K.N.M. Khan
