The Microbiome in Cancer and Autoimmunity - Part A

Erscheinungsjahr 2025
ISBN: 978-0-443-31706-4
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm

Microbiome in Cancer and Autoimmunity - Part A, Volume 394 offers a comprehensive exploration of the intricate relationship between the human microbiome and the development of cancer and autoimmune diseases. Delving into cutting-edge research and clinical insights, this groundbreaking work elucidates the role of microbial communities in influencing immune responses, disease pathways, and therapeutic outcomes. From deciphering the molecular mechanisms underlying microbiome-host interactions to unraveling the impact of dysbiosis on disease progression, the book provides a multifaceted analysis of the microbiome's pivotal role in cancer and autoimmunity.

With contributions from leading experts in the field, this book serves as a pivotal resource for researchers, clinicians, and healthcare professionals seeking to understand and harness the therapeutic potential of the microbiome in combating cancer and autoimmune conditions.

Autoren/Hrsg.

Weitere Mitwirkende

Singh, Manisha

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie

Inhaltsverzeichnis

1. Introduction to Microbiomes in Health and Disease
Santosh Kumar, Prachi Agrawal, Prachi Mendhey, Robins Kumar, Abhishek Dadsena, Prakash Kaushik and Subham Patel
2. Microbiome Dysbiosis in Cancer
Roza Nurieva
3. Role of Microbiomes in Cancer Progression
Sadhna Aggarwal
4. Microbiome-Mediated Immune Modulation in Tumor Microenvironment
Abishai Dominic
5. Microbiome and Cancer Immunotherapy
Shweta Dubey and Mohini Vig
6. The Multipotential Effect of Microbiome in Lung Cancer Development and Progression
Seyed Javad Moghaddam, Nastaran Karimi, Angélica Baca De Anda, Emre Aksan, Maria T. Grimaldo and Rachel Yang
7. Role of microbiome in anti-CAR-T cell therapy
Salah-Eddine Bentebibel and Reham Abdel-Wahab

Über Autor(innen)

Singh, Manisha
Manisha Singh, PhD, is a trained human and mouse immunologist and during the last 10 years, she has specialized in cancer immunology. The main focus of her work has been to increase the efficacy and understand the molecular mechanisms of various cancer immunotherapies. She is serving as the principal investigator on a 2-year grant ($545,486), having been funded by the US Department of Defense. Dr. Singh's current research is focused on understanding the role of inflammation in immune suppression and resistance to immunotherapy in cancer. Recently, she has submitted the NIH-R01 grant in which she proposed to study the role of IL-1? in immunotherapy induced resistance. She has published 24 peer-reviewed articles and many abstracts in prestigious journals such as Nature Communication, Journal of Immunology, and Journal of Clinical Investigator. Her work has been cited by several prestigious, peer-reviewed, international journals.