Novel Platforms for Drug Delivery Applications

Erscheinungsjahr 2022
ISBN: 978-0-323-91376-8
Verlag: William Andrew Publishing

Buch, Englisch, 665 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1000 g

Novel Platforms for Drug Delivery Applications covers diverse aspects in the design, synthesis and characterization of novel drug delivery platforms and devices. This book comprehensively details the development, application and performance of various novel molecular frameworks as potent drug delivery vehicles. Chapters cover a range of materials and molecular platforms for drug delivery, from hydrogels, nanocarriers and metal-organic-frameworks, to ?-cyclodextrin and polyphosphazene. Each chapter discusses the benefits and limitations of each drug delivery system, as well as toxicological and safety implications. This book offers an interdisciplinary approach to this fast-moving topic, bridging the disciplines of materials science and pharmacology.

Zielgruppe

Materials scientists, Pharmaceutical scientists

Autoren/Hrsg.

Thomas, Sabu

Das, Partha Pratim

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

1. Introduction: state of the art, new challenges, and opportunities for drug delivery and its application 2. Drug delivery application: an outlook on past and present technologies 3. General mechanisms of drug loading and sustained release 4. Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing 5. Molecularly imprinted polymeric carriers for controlled drug release 6. Engineered extracellular vesicles as drug delivery systems for the next generation of nanomedicine 7. Polyelectrolyte multilayer films for cancer therapy 8. Porous metal9. Stimulus-responsive liposomes as smart nanocarriers for drug delivery applications 10. Hybrid platforms for drug delivery applications 11. Self-nanoemulsifying drug delivery systems with bioavailability potential 12. Graphene-based nanomaterials for targeted drug delivery and tissue engineering 13. Bionanocomposites as a new platform for drug delivery systems 14. Nanotube platforms for effective drug delivery applications 15. Biodegradable polymeric nanoparticle drug for oral delivery applications 16. Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapy 17. Controlled drug release and drug delivery applications from mesoporous nanoparticles 18. Porous nanostructured metal oxides as potential scaffolds for drug delivery 19. Thin films as an emerging platform for drug delivery 20. Modeling and simulation in drug delivery 21. In-vivo drug release studies 22. Toxicity measurement and toxicity studies of drug delivery 23. Nasal and pulmonary routes of drug delivery 24. "Gene therapy�: ethical and regulatory issues 25. New challenges in drug discovery

Über Autor(innen)

Thomas, Sabu
Prof. Sabu Thomas is the Chairman of the Trivandrum Engineering Science & Technology Research Park (TrEST Research Park) in Thiruvananthapuram, India. Additionally, he is a Professor of Polymer Science and Engineering and the Director of the School of Energy Materials at Mahatma Gandhi University, India. He is the founder director of the International and Inter-university Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University and the former Vice-Chancellor of the same institution.

Prof. Thomas is internationally recognized for his contributions to polymer science and engineering, with his research interests encompassing polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnology, and nano-biomedical sciences have significantly advanced the development of new materials for the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, France.

Das, Partha Pratim
Dr. Partha Pratim Das is presently working as a postdoctoral researcher in Seoul National University, South Korea. He previously worked in the Institute of High-Pressure Mineral Physics and Chemistry, Yonsei University, Seoul, South Korea, as a postdoctoral researcher. He has completed both the B.Sc. (2008) and M.Sc. (2010) in chemistry from Calcutta University, India. He has received Ph.D. in science (chemistry) in 2016 from Jadavpur University, India. His working laboratories during Ph.D. are CSIR-CGCRI, Kolkata, and CSIR-NCL, Pune, India. His research area is focused on nanotechnology, synthesis, and structure-properties correlation studies of different multifunctional nanomaterials under various conditions for mainly clean and sustainable energy and environmental applications. He has published several high-impact papers in peer-reviewed journals. Moreover, his research works have been acclaimed in many national and international conferences and journal societies.