Trebak / Earley Signal Transduction and Smooth Muscle

1. Auflage 2017
ISBN: 978-1-4987-7423-9
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 432 Seiten

Reihe: Methods in Signal Transduction Series

All hollow organs, such as blood vessels, the gastrointestinal tract, airways, male and female reproductive systems, and the urinary bladder are primarily composed of smooth muscle. Such organs regulate flow, propulsion and mixing of luminal contents and storage by the contraction and relaxation of smooth muscle cells. Smooth muscle cells respond to numerous inputs, including pressure, shear stress, intrinsic and extrinsic innervation, hormones and other circulating molecules, as well as autocrine and paracrine factors. This book is a review of smooth muscle cell regulation in the cardiovascular, reproductive, GI, and other organ systems with emphasis on calcium and receptor signaling.

Autoren/Hrsg.

Trebak, Mohamed

Earley, Scott

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

Mitochondrial signaling and smooth muscle function. Imaging Smooth Muscle Ca2+ Signaling in vivo using Mice Geneticallyencoding
biosensors. TIRF microscopy in Vascular smooth muscle. Cytoskeletal Regulation of Smooth Muscle using AFM. Super
resolution microscopy of Ca2+ signals in Smooth Muscle Cells. Signaling by STIM/Orai proteins in Smooth Muscle. Ion Channel
trafficking in Smooth Muscle. Ca2+ sensitization pathways in smooth muscle. Voltage-gated Ca2+ channel Electrophysiology in
Smooth Muscle. Potassium channels in vascular smooth muscle. Lymphatic pacemaking. GI/Bladder Smooth Muscle
pacemaking, regulation and signaling. Micro RNA and lncRNA in smooth muscle function. CRSPR/Cas9 and Smooth musclespecific
knockouts to study Smooth Muscle Differentiation. Ca2+ signaling in Airway smooth muscle reactivity and remodeling.
Inflammation and environmental exposure in Airway smooth muscle. TRP channel function in cerebral smooth muscle. Nox
Inhibitors and smooth muscle tone. Proteomics/Gemonics of smooth muscle. GPCRs and airway smooth muscle function.
Optogentics sensors in mice and smooth muscle signaling.