Valko Physicochemical and Biomimetic Properties in Drug Discovery

Chromatographic Techniques for Lead Optimization
1. Auflage 2014
ISBN: 978-1-118-77041-2
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 450 Seiten, E-Book

Demonstrating how and why to measure physicochemical and biomimetic properties in early stages of drug discovery for lead optimization, Physicochemical and Biomimetic Properties in Drug Discovery encourages readers to discover relationships between various measurements and develop a sense of interdisciplinary thinking that will add to new research in drug discovery. This practical guide includes detailed descriptions of state-of-the-art chromatographic techniques and uses real-life examples and models to help medicinal chemists and scientists and advanced graduate students apply measurement data for optimal drug discovery.

Autoren/Hrsg.

Valko, Klara

Über Autor(innen)

KLARA VALKO is an Investigator in the AnalyticalChemistry Department of Molecular Discovery Research atGlaxoSmithKline. Dr. Valko has more than thirty years of experiencein HPLC, GC, and LC/MS. She also has more than ten years ofexperience teaching physicochemical measurements and ADMEoptimization tools at the UCL School of Pharmacy. Currently, Dr.Valko is an Honorary Professor, leading the Physchem/ADME modulefor a drug discovery MSc course.