Van Bruggen / Roberts Biomedical Imaging in Experimental Neuroscience

Erscheinungsjahr 2002
ISBN: 978-1-4200-4215-3
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 368 Seiten

Reihe: Frontiers in Neuroscience

Recent years have seen an explosion of activity in the field of biomedical imaging in an attempt to understand the behavior of the brain in healthy and disease states. With the emergence of genetically manipulated laboratory mice and the knowledge of the mouse genome, we are entering an exciting new era with revolutionary tools for experimental research. Noninvasive imaging techniques capable of providing both anatomical and functional descriptions of the brain have become essential. Among the various imaging methodologies, magnetic resonance imaging (MRI) stands in the forefront by virtue of its contrast versatility and pathophysiological specificity.

Emphasizing the relationship between physiological microenvironment and macroscopic imaging signal changes, Biomedical Imaging in Experimental Neuroscience presents a comprehensive review of the noninvasive biomedical imaging techniques available for laboratory animal research. Focusing on MRI, but recognizing the multiple forms of imaging information, this book outlines the scope and limitations of these methods and analyzes their impact on in vivo neuroscience research. The book is intended for the biologist who may not have a background in the physical sciences. This applied guide also provides a concise theoretical description of the pertinent physics.

Noninvasive imaging offers the obvious benefits of reducing sample sizes and identifying new and unanticipated behaviors. Biomedical Imaging in Experimental Neuroscience presents detailed information for biologists interested in how biomedical imaging may augment their in vivo research and for clinical practitioners seeking deeper insights into the association between imaging findings and disease pathophysiology.

Zielgruppe

Experimental neuroscientists, researchers, graduate and post graduate students, clinical scientists, basic scientists in neuroscience and neurobiology, laboratory animal science researchers

Autoren/Hrsg.

Van Bruggen, Nick

Roberts, Timothy P.L.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Principles of MRI Contrast, Tim Roberts and Nick van Bruggen

MRI Measurement of Cerebral Perfusion and Application to Experimental Neuroscience, Mark F. Lythgoe, D.L.Thomas, and F. Calamante

MRI Measurement of Cerebral Water Diffusion and Its Application to Experimental Research, Richard A. D. Carano, Nick van Bruggen and Alex J. de Crespigny

Functional Magnetic Resonance Imaging, Mathias Höehn.

Functional Imaging in Nonhuman Primates, Elizabeth Disbrow

Pharmacologic Magnetic Resonance Imaging (phMRI), Bruce G. Jenkins, Yin-Ching Iris Chen, and Joseph B. Mandeville

Anatomical Studies in the Rodent Brain and Spinal Cord: Applications of Magnetic Resonance Microscopy, Helene Benveniste, Tom Mareci, and Steve Blackband

Magnetic Resonance Spectroscopy: Principles and Applications, Stephen R. Williams and Nicola R. Sibson.

Small Animal Imaging with Positron Emission Tomography, Simon Cherry and Harley Kornblum

MRI and Novel Contrast Agents for Molecular Imaging, Michel M. Modo and Steven C.R. Williams

The Future for Biomedical Imaging: Emerging and Alternative Technologies, Nick van Bruggen and Tim Roberts