CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

1. Auflage 2022
ISBN: 978-0-367-54286-3
Verlag: CRC Press

Buch, Englisch, 268 Seiten, Format (B × H): 159 mm x 235 mm, Gewicht: 538 g

The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases is a unique reading material for college students, academicians, and other health professionals interested in learning about the broad range of applications of CRISPR/Cas9 genetic scissors. Some topics included in this book are: the role of the CRISPR/Cas9 system in neuroscience, gene therapy, epigenome editing, genome mapping, cancer, virus infection control strategies, regulatory challenges and bioethical considerations.

Autoren/Hrsg.

Vaschetto, Luis María

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Mathematik | Informatik Mathematik Stochastik

Inhaltsverzeichnis

1. The CRISPR/Cas9 Genome-editing System: Principles and Applications 2. Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing 3. Gene Editing and Genetic Disorders: Ethical and Legal Concerns 4. Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology 5. CRISPR/Cas and Gene Therapy: An Overview 6. CRISPR and Cancer: From Bench to Clinic 7. The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System 8. CRISPR/Cas9 Technology as a Strategy Against Viral Infections 9. CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research 10. Non-viral Alternatives to Delivery of CRISPR-Cas Gene Editing Components 11. CRISPR Medicine: Advance, Progress and Challenges

Über Autor(innen)

Luis María Vaschetto received his Doctorate in Biological Sciences from Universidad Nacional de Córdoba (Argentina). He was a postdoctoral researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a research associate at South Dakota State University (SDSU). His research focuses on understanding the epigenetic mechanisms involved in plant and animal development, as well as their effects on human health and diseases.