Chinmedomics

The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine
Erscheinungsjahr 2015
ISBN: 978-0-12-803117-9
Verlag: Elsevier Science

Buch, Englisch, 408 Seiten, Format (B × H): 191 mm x 236 mm, Gewicht: 1021 g

Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future.

Zielgruppe

Pharmacologists, drug developers, medicinal plant researchers and pharmacognosists, researchers of traditional medicines and natural product chemistry, researchers studying metabolomics and biomarkers and analytical chemists

Autoren/Hrsg.

Wang, Xijun

Zhang, Aihua

Sun, Hui

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Komplementäre Medizin, Asiatische Medizin (TCM), Heilpraktiker
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie

Inhaltsverzeichnis

Preface
- Origin of Chinmedomics
- Methods and protocols of Chinmedomics
- Chinmedomics advancing drug discovery and development from Yinchenhao Tang
- Chinmedomics approach dissects therapeutic properties of ShenQiWan acting on ShenYangXu syndrome
- Metabolic profiling and biomarkers analysis of Jaundice syndrome
- Metabolic profiling and biomarkers analysis of GanYuPiXU syndrome
- Metabolic profiling and biomarkers of Yinhuang syndrome and evaluation on Yinchensini Tang
- Metabolite profiling and biomarkers analysis of Jaundice syndrome related animal model
- Metabolomic evaluation of hepatoprotective effect of Yinchenhao Tang and its major bioactive constituents
- Metabolomics and proteomics elucidation on therapeutic mechanisms of geniposide
- Metabolic profiling and potential biomarkers of ShenYinXu syndrome and therapeutic effect of Liuweidihuang Wan
- Metabolic profiling of healthy persons treated with Liuweidihuang Wan
- Metabolic profiling and potential biomarkers analysis of ShenYangXu syndrome
- Metabolic evaluation of ShenQiWan nourishing ShenYangXu syndrome
- Metabolic profiling and biomarkers analysis of XinQiXu syndrome
- Active constituents screening based on correlation analysis between marker metabolites and absorbed constituents in Wen-Xin-Formula
- Targeted synergism effects of the combined active constituents of Yinchenhao Tang
- Metabolic profiling and biomarkers of type 2 diabetes and effective evaluation of Tianqi Jiangtang capsule
- Metabolic biomarkers of alcohol liver damage and intervention effect of Yinchenhao Tang
- Metabolic profiling and biomarkers analysis of insomnia and intervention effects of Suanzaoren decoction and its related active ingredients
- Metabolic biomarkers of nonbacterial prostatitis and treatment evaluation of Phellodendri amurensis cortex and its main components
- Metabolic profiling provides a system for understanding of Alzheimer's disease in rats after treatment with Kaixin San
- Metabolic profiles delineate the effect of Shengmai San on Alzheimer's disease in rats

Über Autor(innen)

Wang, Xijun
Xijun Wang, PhD, is a Professor of Pharmacology of Traditional Chinese Medicine (TCM) and Vice President at Heilongjiang University of Chinese Medicine in China. Dr. Wang has published more than 150 papers in peer-reviewed journals, received the National Science and Technology Progress Award and National Technological Invention Award and holds 20 patents. His research focuses on serum Pharmacochemistry of Traditional Chinese Medicines. By integrating metabolomics with serum Pharmacochemistry of TCM Dr. Wang has developed and established the theory and research methods of Chinmedomics, whereby the clinical efficacy of TCM formulae can be measured and analyzed.