High-Yield™ Biochemistry

Third
ISBN: 978-0-7817-9924-9
Verlag: Lippincott Williams and Wilkins

Buch, Englisch, 128 Seiten, Trade Paper, Format (B × H): 178 mm x 254 mm, Gewicht: 249 g

Reihe: High-Yield Series

Part of the popular High-Yield™ Series, this updated Third Edition provides a succinct, heavily illustrated review in outline format of medical biochemistry for students preparing for USMLE Step 1. Highlights of this edition include revised and updated chapters on gene expression and biomedical technology. More clinical correlates have been added throughout the text.

Autoren/Hrsg.

Wilcox, R. Bruce

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie

Inhaltsverzeichnis

Preface
Acknowledgments
1 Acid-Base Relationships
- I.Acidic dissociation

- II.Measures of acidity

- III.Buffers

- IV.Acid-base balance

- V.Acid-base disorders

- VI.Clinical relevance: diabetic ketoacidosis

2 Amino Acids and Proteins
- I.Functions of proteins

- II.Proteins as polypeptides

- III.Protein structure

- IV.Protein solubility and R-groups

- V.Protein denaturation

- VI.Clinical relevance

3 Enzymes
- I.Energy relationships

- II. Free-energy change

- III.Enzymes as biological catalysts

- IV. Michaelis-Menten equation

- V. Lineweaver-Burk equation

- VI.Enzyme
regulation
- VII.Clinical relevance: methanol and ethylene glycol poisoning

4 Citric Acid Cycle and Oxidative Phosphorylation
- I.Cellular energy and adenosine triphosphate

- II.Citric acid cycle

- III.Products of the citric acid cycle (one revolution)

- IV.Synthetic function of the citric acid cycle

- V.Regulation of the citric acid cycle

- VI.Electron transport and oxidative phosphorylation

- VII.Chemiosmotic hypothesis

- VIII.Clinical relevance

5 Carbohydrate Metabolism
- I.Carbohydrate digestion and absorption

- II. Glycogen metabolism

- III. Glycolysis

- IV. Gluconeogenesis

- V. Regulation of glycolysis and gluconeogenesis

- VI. Pentose phosphate pathway

- VII.Sucrose and lactose metaboli sm

- VIII. Clinical relevance

6 Lipid Metabolism
- I.Lipid function

- II.Lipid digestion

- III.Lipoprotein transport and metabolism

- IV. Oxidation of fatty acids

- V.Fatty acid synthesis

- VI. Glycerolipid synthesis

- VII.Sphingolipid synthesis

- VIII.Cholesterol synthesis

- IX. Clinical relevance

7 Amino Acid Metabolism
- I. Functions of amino acids

- II. Removal of amino acid nitrogen

- III.Urea cycle and detoxification of NH+

- IV.Carbon skeletons of amino acids

- V.Clinical relevance: inherited (inborn) errors of amino acid metabolism

8 Nucleotide Metabolism
- I.Nucleotide structure

- II.Nucleotide function

- III. Purine nucleotide synthesis

- IV. Pyrimidine nucleotide synthesis

- V.Deoxyribonucleotide synthesis

- VI.Nucleotide degradation

- VII.Clinical relevance

9 Nutrition
- I.Energy needs

- II.Macronutrients

- III.Micronutrients: the fat-soluble vitamins

- IV.Micronutrients: the water-soluble vitamins

- V.Minerals

10 Gene Expression
- I.Genetic information

- II.DNA and RNA: nucleic acid structure

- III.DNA synthesis (replication)

- IV.Transcription

- V.Translation (protein synthesis)

- VI.Mutations

11 Biochemical Technology
- I.Protein purification

- II.Protein analysis

- III.DNA analysis

- IV.Cloning of recombinant DNA and protein

- V.Clinical relevance

12 Hormones
- I.Overview

- II.Classification of hormones

- III.Mechanisms of hormone action

- IV.Hormones that regulate fuel metabolism

- V.Hormones that regulate salt and water balance

- VI.Hormones that regulate calcium and phosphate metabolism

- VII.Hormones that regulate body size and metabolism

- VIII.Hormones that regulate the male reproductive system

Abbreviated Table of Contents