Tissue and Organ Regeneration in Adults

Extension of the Paradigm to Several Organs
2. 2015 Auflage 2014
ISBN: 978-1-4939-1864-5
Verlag: Springer

Buch, Englisch, 332 Seiten, Format (B × H): 161 mm x 244 mm, Gewicht: 7276 g

This textbook describes the basic principles of induced organ regeneration in skin and peripheral nerves and extends the original successful paradigm to other organs. A set of trans-organ rules is established and its use in regeneration of several organs is illustrated from the works of several independent investigators who worked with a variety of organs, such as the lung, the bladder, and the Achilles tendon, using collagen-based scaffolds somewhat similar to the original one. These critical medical treatments fill the clinical need that is not met by organ transplantation.

New to this second edition:

New information extending the paradigm of tissue regeneration from organ regeneration in skin and peripheral nerves to other organs

Guidelines, known as trans-organ rules, are described for the first time for extending this unique medical treatment to organs of several medical specialties

The work serves as a comprehensive text and reference for students and practitioners of tissue engineering

Zielgruppe

Graduate

Autoren/Hrsg.

Yannas, Ioannis V

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Dermatologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

The Irreversibility of Organ Injury.- Nonregenerative Tissues.- Experimental Methods I. The Anatomically Well-Defined Wound.- Experimental Methods II. The Defect Closure Rule.- Regeneration of Skin.- Regeneration of a Peripheral Nerve.- Minimum Reactants Required for Synthesis of Skin and Peripheral Nerves; Extension to Tissues of Other  Organs.- An Antagonistic Relation Between Wound Contraction and Regeneration.- Molecular biology of contraction blockade by active scaffolds.- The Scaffold Regeneration Paradigm and its Consequences.

Über Autor(innen)

Dr. Ioannis V. Yannas is a professor of Mechanical and Biological Engineering at MIT.