E-Book, Englisch, 275 Seiten
Zapico Mechanisms Linking Aging, Diseases and Biological Age Estimation
1. Auflage 2017
ISBN: 978-1-4987-0970-5
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
E-Book, Englisch, 275 Seiten
ISBN: 978-1-4987-0970-5
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
ASPARTIC ACID RACEMIZATION
Introduction to Aspartic Acid Racemization
Christian Thomas and Sara C. Zapico
Aspartic Acid Racemization on Aging
Sara C. Zapico, Christian Thomas and Sofía Tirados Menéndez
Aspartic Acid Racemization and Aging in Cartilaginous Tissue
Sarit Sara Sivan, Alice Maroudas and Ellen Wachtel
Racemization and Isomerization of Aspartyl Residues in Amyloid Peptides Involved in the Development of Alzheimer´s Disease
Koichi Inoue and Toshimasa Toyo’oka
Aspartic Acid Racemization: Applications to Forensic and Archaeological Age Estimation
Rebecca C. Griffin and Matthew Collins
ADVANCED GLYCATION ENDPRODUCTS
Advanced Glycation Endproducts: An Introduction
Andreas Simm and Alexander Navarrete Santos
Advanced Glycation and Aging
Alejandro Gugliucci
AGE-RAGE Axis in the Aging and Diabetic Heart: Prime Target for Adjunctive Therapeutic Intervention
Karen M. O’Shea, Ann Marie Schmidt and Ravichandran Ramasamy
Advanced Glycation Endproducts in Aging Skin
Paraskevi Gkogkolou and Markus Böhm
Advanced Glycation Endproducts and Neurological Diseases
Teresita Menini
Advanced Glycation Endproducts for Age at Death Estimation
Luis L. Cabo, Christian Thomas and Sara C. Zapico
TELOMERES
Introduction to Telomere Biology
Celia de Frutos and Pablo Bermejo-Álvarez
Role of Telomeres in Aging
Christian Thomas and Sara C. Zapico
Telomeres and Cardiovascular Disease: Facts, Controversies and Limitations
Vicente Andrés, Beatriz Dorado and Ioakim Spyridopoulos
Telomeres in Cancer
João Vinagre, Ana Pestana, Manuel Sobrinho-Simões and Paula Soares
Forensic Application of Telomere Shortening in Age-at-death Estimation
Joe Adserias-Garriga
MITOCHONDRIAL DNA MUTATIONS
Introduction to Mitochondria Biology
Christian Thomas and Sara C. Zapico
Mitochondrial DNA Mutations and Aging
Rebecca Stone Gordon and Sara C. Zapico
Mitochondrial DNA Mutations and Mitochondrial Diseases
María Elena Gómez-Gómez
Reproductive Approaches to Prevent the Transmission of Mitochondrial Diseases
María Jesús Sánchez-Calabuig, Noelia Fonseca Balvís, Serafín Pérez-Cerezales and Pablo Bermejo-Álvarez
Mitochondrial DNA Mutations and Neurodegenerative Diseases
Paula Núñez
An Overview of mtDNA Analysis for Age-at-death Estimation in Forensic Sciences
Silvia Zoppis
EPIGENETICS
Epigenetics: Its Role in Aging, Diseases and Biological Age Estimation
Christian Thomas and Sara C. Zapico
