Preparation and Quality Control in Nuclear Medicine
Buch, Englisch, 345 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 717 g
ISBN: 978-3-540-33989-2
Verlag: Springer Berlin Heidelberg
Radioactive drug development is a multi-disciplinary task, therefore, in a concerted effort, dedicated scientists and experts from different fields of specialisation have contributed to this book. It is presented in two sections. Section 1 contains basic principles and methods used for analysis, information on the chemistry of technetium and on radiopharmaceuticals labelled with technetium-99m, the characteristics of the 99 Mo/99mTc-generator, of 'kits' and formulations for in-vitro labelling, and special safety aspects for in-vivo labelling of blood cells. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affecting in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Nuklearmedizin, PET, Radiotherapie
Weitere Infos & Material
I.- Drug Safety.- Technetium in Medicine.- Stannous Chloride in the Preparation of 99mTc Pharmaceuticals.- Quality Assurance of Radiopharmaceuticals.- Performance and Quality Control of the 99Mo/99mTc Generator.- Preparation of Technetium 99mTc Pharmaceuticals.- Lyophilization Technique for Preparing Radiopharmaceutical Kits.- Cellular Labeling with 99mTc Chelates: Relevance of In Vitro and In Vivo Viability Testing.- Quality Control Methods of 99mTc Pharmaceuticals.- Other Technetium Isotopes: 94mTc as a Potential Substitute in Positron Emission Tomography Investigations.- The Rules Governing Medicinal Products for Human Use in the European Union.- II.- Monographs of 99mTc Pharmaceuticals.
