Stability of Protein Pharmaceuticals

Part B: In Vivo Pathways of Degradation and Strategies for Protein Stabilization
1992. Auflage 1992
ISBN: 978-0-306-44153-0
Verlag: Springer Us

Buch, Englisch, Band 3, 328 Seiten, Format (B × H): 161 mm x 236 mm, Gewicht: 1500 g

Reihe: Pharmaceutical Biotechnology

Part B explores protein degradation occuring in vivo during protein synthesis in cells, examines the isolation and purification of proteins, details protein use in organisms, and reviews techniques to enhance protein stability.

Zielgruppe

Research

Autoren/Hrsg.

Ahern, Tim J

Manning, Mark C

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Kosmetische Technologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

Improper Glycosylation and the Cellular Editing of Nascent Proteins; D.A. Cumming. Protein Aggregation In Vivo; R. Wetzel. Pathways of Intracellular Protein Degradation in Eukaryotic Cells; T.S. Olson, et al. Effects of Aging on Proteins; R.W. Gracy. Engineering Dramatic Increases in the Stability of Subtilisin; P.N. Bryan. Increased Stability of Mutant Forms of Yeast Cytochrome c; D.R. Hickey, et al. Introduction to Formulation of Protein Pharmaceuticals; M.A. Hanson, S.K.E. Rouan. PEG Modified Proteins; G.E. Francis, et al. Stabilization of Protein Structure by Solvent Additives; S.N. Timasheff. Heat-Shock Proteins and their Potential Uses for Pharmaceutical Protein Production in Microorganisms; J.M. McCoy. Index.