Animal Models of Disease Part B

Erscheinungsjahr 2024
ISBN: 978-0-443-22240-5
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Animal Models of Disease, Part B, Volume 188 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Using C. Elegans as a model for Neurodegenerative disease: Methodology and Evaluation, Modelo Animal de Esclerosis Multiple: Encefalomielitis Autoimmune Experimental (EAE, New mouse model to study aneurysm development, Spinal Nerve Ligation: An Experimental Neuropathic Pain Model in Rats and Mice, Identifying therapeutic compounds for Autosomal Dominant Optic Atrophy (ADOA) through screening in the nematode C. elegans, Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia, and much more.

Other chapters cover Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis, Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models, Assessing motor development and function in mouse models of neurodevelopmental disorders, Analysis of Gut Microbiota profile targeted to multi hypervariable regions of 16S rRNA in hypertensive heart failure rat model, and more.

Autoren/Hrsg.

Weitere Mitwirkende

Martinez, Aitziber Buque

Bravo-San Pedro, Jose Manuel

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Entwicklungsbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

Preface Lorenzo Galluzzi, Fernando Aranda Vega, Aitziber Buque Martinez and Jose Manuel Bravo-San Pedro

1. Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation Elena Caldero-Escudero, Silvia Romero-Sanz and Sergio De la Fuente

2. Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis Ana Muñoz-Jurado, Begoña Escribano and Isaac Túnez

3. A new procedure to induce aortic aneurysms in mice Raquel Rodrigues-Díez, Antonio Tejera-Muñoz and Raúl R. Rodrigues-Diez

4. Spinal nerve ligation: An experimental model to study neuropathic pain in rats and mice Erick J. Rodríguez-Palma, Itzel I. Ramos-Rodríguez, Saúl Huerta de la Cruz, Vinicio Granados-Soto and Maria Sancho

5. Identifying therapeutic compounds for autosomal dominant optic atrophy (ADOA) through screening in the nematode C. elegans Fivos Borbolis and Konstantinos Palikaras

6. Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia Iria Fernandez Botana, Susanne Gonder, Vanessa Klapp, Etienne Moussay and Jerome Paggetti

7. Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis Laura Amo, Hemanta K. Kole, Bethany Scott, Francisco Borrego, Chen-Feng Qi, Hongsheng Wang and Silvia Bolland

8. Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models Sara Lamorte, Alisha R. Elford, Douglas C. Chung, Kiichi Murakami, Tracy L. McGaha and Nicolas Jacquelot

9. Assessing motor development and function in mouse models of neurodevelopmental disorders Lauren Dierdorff, Marta Garcia-Forn, Alexa von Mueffling and Silvia De Rubeis

10. Analysis of the gut microbiota profile targeted to multiple hypervariable regions of 16S rRNA in a hypertensive heart failure rat model Javier Modrego, Adriana Ortega-Hernández, Silvia Sánchez-González, Arturo Corbatón-Anchuelo and Dulcenombre Gómez-Garre

11. Animal models of neglected parasitic diseases: In vivo multimodal imaging of experimental trypanosomatid infections Jean Marc Tsagmo Ngoune, Brice Rotureau and Estefanía Calvo Alvarez

12. Intracranial graft of bioresorbable polymer scaffolds loaded with human dental pulp stem cells in stab wound murine injury model Irene Manero-Roig, Yurena Polo, Beatriz Pardo-Rodríguez, Jon Luzuriaga, Ruth Basanta-Torres, Daniel Martín-Aragón, Irene Romayor, Sara Martín-Colomo, Joana Márquez, Laura Gomez-Santos, Frédéric Lanore, Yann Humeau, Gaskon Ibarretxe, Cristina Eguizabal, Aitor Larrañaga and Jose Ramon Pineda

Über Autor(innen)

Martinez, Aitziber Buque
Aitziber Buqué is currently a Post-Doctoral Associate with the Galluzzi Lab, in the Department of Radiation Oncology at Weill Cornell Medical College (New York), where she investigates innate and acquired mechanisms of resistance to immunotherapy in HR+ breast cancer and radiotherapy as a means to overcome them. Prior to joining the Galluzzi Lab (2018), Aitziber was a Post-Doctoral Associate with the Kroemer Lab in the Cordeliers Research Center (Paris, France; 2014-2018), after receiving her M.Sc. in Bioinformatics and Computational Biology (2006) from the Complutense University (Madrid, Spain) and her Ph.D. in Biomedicine (2013) from the BioCruces Research Institute (Barakaldo, Spain). Aitziber has a long-standing interest in the immunological mechanisms controlling cancer progression and response to treatment.

Bravo-San Pedro, Jose Manuel
Jose Manuel Bravo-San Pedro is currently a researcher at the Department of Physiology of the Complutense University of Madrid thanks to a Ramon y Cajal contract grant. He got his Ph.D. in biochemistry, cellular biology and genetics from the University of Extremadura (Caceres, Spain) in 2011, and he did a post-doctoral stage in the laboratory of Prof. Guido Kroemer. His main research interests have always been linked to autophagy, addressing this cellular process associated with neurodegenerative diseases or cancer and recently obesity and specifically related to problems in the correct functioning of the cilium. He is co-inventor of two patents and co-author of 110 publications indexed in PubMed in prestigious international journals, with h-index 45 and 23768 cites (Dec 2022).