Buch, Englisch, 412 Seiten, Format (B × H): 165 mm x 240 mm, Gewicht: 960 g
Buch, Englisch, 412 Seiten, Format (B × H): 165 mm x 240 mm, Gewicht: 960 g
ISBN: 978-1-55938-809-2
Verlag: Elsevier Science & Technology
The last twenty years have seen remarkable growth in our knowledge of molecular genetics, most of which is the outcome of recombinant DNA technology. This technology which is not limited to cloning, sequencing, and expression has created a biotechnology industry of its own, the purpose of which is to develop new diagnostic and therapeutic approaches in medicine. Both industries in collaboration with the biomedical community are now engaged in laying down the foundation of molecular medicine.
The present volume seeks to provide a coherent account of the new science of molecular genetics. Its content however is by no means exhaustive, partly because of the publication explosion but more because of space restrictions. A rudimentary knowledge of genetics on the reader's part is assumed. Quite understandably, considerable emphasis is placed on major technical advances but not without expounding numerous new ideas and phenomena including alternative splicing, POR, DNA methylation, genomic imprinting, and so on.
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tiergenetik, Reproduktion
- Naturwissenschaften Biowissenschaften Humanbiologie
- Naturwissenschaften Biowissenschaften Molekularbiologie
- Naturwissenschaften Biowissenschaften Proteinforschung
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer
- Naturwissenschaften Biowissenschaften Botanik Pflanzenreproduktion, Verbreitung, Genetik
- Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
- Naturwissenschaften Biowissenschaften Zellbiologie
Weitere Infos & Material
Preface (E.E. Bittar and N. Bittar). The Nucleosome (R.D. Kornberg). DNA Replication and its Control (J. blow and J.P.J. Chong). DNA Methylation (R.L.P. Adams). Role of Histones and their Acetylation in Control of Gene Expression (B.M. Turner). Protein-Nucleic Acid Recognition and Interactions (A. Vrielink and P.S. Freemont). Transcription Factors (D.S. Latchman). Alternative RNA Splicing (D.S. Latchman). Antisense RNA and DNA as Potential Therapeutic Agents (L.J. Van Eldik). Regulation of Gene Expression and Gene Amplification (J.D. Hawkins and I.R. Philips). Signal Transduction to the Cell Nucleus (E.A. Nigg). DNA DAmage and Its REpair (A.R. Collins). The Nature and Significance of Mutations (A.R. Collins). The Polymerase Chain Reaction (K.A. Eidne and E. Faccenda). Molecular Cloning (K.A. Eidne). DNA Probes in Human Diseases (P.M. Brickell). Advances in Clinical Genetics (R.S. Verma). The Genome Project-A Commentary (D.R.J. Macer). Transgenic Regulation in Laboratory Animals (S. Rusconi).