Discovery and Development of Anti-Breast Cancer Agents from Natural Products

Erscheinungsjahr 2021
ISBN: 978-0-12-821277-6
Verlag: William Andrew Publishing

Buch, Englisch, 384 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Discovery and Development of Anti-Breast Cancer Agents from Natural Products presents cutting-edge research advances in the field of bioactive natural products and natural drug formulations. This volume in the Natural Products Drug Discovery series focuses on molecules of natural origin and their synthetic analogs that show promising potential to act as anti-breast cancer and chemotherapeutic agents. Combining foundational background information on cancer mechanisms with details of medicinal structures from natural products, this volume compiles the latest developments from across interdisciplinary fields.

Discovery and Development of Anti-Breast Cancer Agents from Natural Products will serve as a valuable resource for researchers working to discover promising leads for the development of novel pharmaceuticals for breast cancer, highlighting a number of key structures from natural products and exploring possible future developments in the area.

Zielgruppe

Medicinal chemists, Synthetic Chemists, Phytochemists, Combinatorial Chemists, Pharmacologists, Biochemists, Cancer researchers, Botanists, Students in related fields

Autoren/Hrsg.

Brahmachari, Goutam

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Naturwissenschaften Chemie Organische Chemie

Inhaltsverzeichnis

1. Discovery and Development of Anti-Breast Cancerous Agents From Natural Products: An Overview
2. Epothilones A and B: The 16-Membered Natural Macrolides as a Fascinating Template for Antibreast Cancer Drug Discovery
3. Anti-Breast Cancer Terpenoids of Natural Origins
4. Vinca Alkaloids as Chemotherapeutic Agents Against Breast Cancer
5. Cannabinoids and Breast Cancer
6. Carotenoids as Tools in Breast Cancer Therapy
7. Flavonoids as Inducers of Apoptosis and Autophagy in Breast Cancer
8. Phytoestrogens as Novel Therapeutic Molecules Against Breast Cancer
9. Chemopreventive and Therapeutic Potential of Natural Agents and Their Combinations for Breast Cancer
10. Nanoparticles for Delivering Natural Product Chemotherapeutics to Breast Cancer Cells
11. Molecular Mechanisms Underlying Breast Cancer and Role of Plant Products in Targeted Therapy

Über Autor(innen)

Brahmachari, Goutam
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series 'Natural Product Drug Discovery'. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).