Computer Methods, Part C

Erscheinungsjahr 2011
ISBN: 978-0-12-381270-4
Verlag: William Andrew Publishing

Buch, Englisch, 696 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 1210 g

The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with the 2 previous Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.

Zielgruppe

<p>Biochemists, molecular biologists, cell biologists, biomedical researchers, microbiologists, and developmental biologists</p>

Autoren/Hrsg.

Weitere Mitwirkende

Simon, Melvin I.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien

Inhaltsverzeichnis

- Predicting Fluorescence Lifetimes and Spectra of Biopolymers

Patrik R. Callis

- Modeling of Regulatory Networks: Theory and Applications in the study of the Drosophila Circadian Clock

Elizabeth Y. Scribner, Hassan M. Fathallah-Shaykh

- Strategies for articulated multibody-based adaptive coarse grain simulation of RNA

Mohammad Poursina, Kishor D. Bhalerao, Samuel C. Flores, Kurt S. Anderson, Alain Laederach

- Modeling Loop Entropy

Gregory S. Chirikjian

- Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles

Radhakrishnan Nagarajan

- Numerical solution of the chemical master equation: uniqueness and stability of the stationary distribution for chemical networks, and mRNA bursting in a gene network with negative feedback regulation

E. S. Zeron, M. Santill_an

- How molecular should your molecular model be? On the level of molecular detail required to simulate biological networks in systems and synthetic biology

Didier Gonze, Wassim Abou-Jaoud´e, Adama Ouattara, and Jos´e Halloy

- Computational modelling of biological pathways by executable biology

Maria Luisa Guerriero John K. Heath

- Computing Molecular Fluctuations in Biochemical Reaction Systems Based on A Mechanistic, Statisitical Theory of Irreversible Processes

Don Kulasiri

- Probing the input-output behaviour of biochemical and genetic systems: system identification methods from control theory

David McMillen, Brian Ingalls, Jordan Ang

- Biochemical pathway modelling tools for drug target detection in cancer and other complex diseases

Alberto Marin-Sanguino, Shailendra K. Gupta, Eberhard O. Voit and Julio Vera

- Deterministic and Stochastic Simulation and Analysis of Biochemical Reaction Networks: The Lactose Operon Example

Necmettin Yildirim, Caner Kazanci F

- Multivariate Neighborhood Sample Entropy: A method for data reduction and prediction of complex data.

Joshua S. Richman MD, PhD

- Scaling differences of heartbeat excursions between wake and sleep periods

L. Guzm´an-Vargas, I. Reyes-Ram´irez, R. Hern´andez-P´erez, F. Angulo-Brown

- Changepoint analysis for single-molecule polarized totalinternal reflection fluorescence microscopy experiments

John F. Beausang, Yale E. Goldman, and Philip C. Nelson

- Inferring mechanisms from dose-response curves

Carson C. Chow, Karen M. Ong, Edward J. Dougherty, and S. Stoney Simons, Jr.

- Spatial Aspects in Biological System Simulations

Haluk Resat, Michelle N. Costa, and Harish Shankaran

- Computational Approaches to Modeling Viral Structure and Assembly

Stephen C. Harvey, Anton S. Petrov, Batsal Devkota and Mustafa Burak Boz

- An Object-Oriented Software Suite for the Simulation and Design of Macromolecules

Andrew Leaver-Fay, Michael Tyka, Steven M. Lewis, Oliver F. Lange, James Thompson, Ron Jacak, Kristian Kaufman, P. Douglas Renfrew, Colin A. Smith, Will Sheffler, Ian W. Davis, Seth Cooper, Adrien Treuille, Daniel J. Mandell, Florian Richter, Yih-En Andrew Ban, Sarel J. Fleishman, Jacob E. Corn, David E. Kim, Sergey Lyskov, Monica Berrondo, Stuart Mentzer, Zoran Popovic, James J. Havranek, John Karanicolas, Rhiju Das, Jens Meiler, Tanja Kortemme, Jeffrey J. Gray, Brian Kuhlman1, David Baker, and Philip Bradley

- Computational Design of Intermolecular Stability and Specificity in Protein Self-Assembly

Vikas Nanda, Sohail Zahid, Fei Xu, Daniel Levine