Handbook of Pharmacokinetic/Pharmacodynamic Correlation

1. Auflage 2019
ISBN: 978-0-367-22803-3
Verlag: Taylor & Francis Ltd

Buch, Englisch, 483 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 1075 g

Reihe: Routledge Revivals

First published in 1995: Combining the established disciplines of pharmacokinetics (PK), the relationship between drug concentration and time, and pharmacodynamics (PD), the relationship between drug effects and concentration, this handbook examines the relevant relationship between drug effects and time.

Autoren/Hrsg.

Derendorf, Hartmut

Hochhaus, Günther

Hochhaus, Guenther

Weitere Mitwirkende

Nolting, Arno

Mollmann, Helmut

Snoeck, Eric

Van Peer, Achiel

Heykants, Joseph

Tzeng, Tang-bin

Danhof, Meindert

Voskuyl, Rob A.

Walker, Judith S.

Schmith, Virginia D.

Muir, Keith T.

Ebert, Steve

Lalonde, Richard L.

Gupta, Samir K.

Ellinwood, Everett H.

Evans, W. E.

McLeod, Howard L.

Venitz, Jurgen

Mungall, Dennis

Fleishaker, Joseph C.

Ferry, James J.

Fung, Ho-Leung

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Pharmacokinetic-Pharmacodynamic Modeling of Reversible Drug Effects
J. Venitz
2. Pharmacokinetic-Pharmacodynamic Modeling of Irreversible Drug Effects
S. Ebert
3. Pharmacokinetic-Pharmacodynamic Modeling in Drug Development: Comments and Applications
J. Fleishaker and J. Ferry
4. Dose Optimization Based on Pharmacokinetic-Pharmacodynamic Modeling
G. Hochhaus and H. Derendorf
5. Pharmacokinetic-Pharmacodynamic Correlations of Anesthetics Agents
V.D. Schmith and K. Muir
6. Pharmacokinetic-Pharmacodynamic Correlations of Analgesics
J.S. Walker
7. Pharmacokinetic-Pharmacodynamic Correlations of Benzodiazepines
S.K. Gupta
8. Pharmacokinetic-Pharmacodynamic Correlations of Anticonvulsants
M. Danhof and R. Voskuyl
9. Pharmacokinetic-Pharmacodynamic Correlations of Cardiovascular Drugs
R. Lalonde
10. Pharmacokinetic-Pharmacodynamic Correlations of Selected Vasodilators
T.-B. Tzeng and H.-L. Fung
11. Pharmacodynamics Correlations of Anticoagulants
D. Mungall and R.H. White
12. Pharmacokinetic-Pharmacodynamic Correlations of Antihistamines
E. Snoeck, A. Van Peer, and J. Heykants
13. B2-Agonists: Terbutaline, Albuterol, and Fenoterol
G. Hochhaus and H. Mllmann
14. Pharmacokinetic-Pharmacodynamic Correlations of Corticosteriods
H. Mllmann et al.
15. Pharmacokinetic-Pharmacodynamic Modeling of Antibiotics
A.Nolting and H. Derendorf
16. Clinical Pharmacodynamics of Anticancer Drugs
H.L. McLeod and W.E. Evans
17. Computer Applications in Clinical Pharmacokinetics and Pharmacodynamics
D. Mungall, J. Heissler, and M. Kaltenbach

Über Autor(innen)

Hartmut Derendorf, Ph.D., is Professor and Chairman of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.
Gunther Hochhaus, Ph.D., is Associate Professor of the Department of Pharmaceutics in the College of Pharmacy, University of Florida in Gainesville, Florida.