Control of Cell Cycle and Cell Proliferation, Volume 135 in the Advances in Protein Chemistry and Structural Biology series, presents chapters on a variety topics, including Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest, Viral infection on through Cell Cycle Regulation, Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach, Controlling cell proliferation by targeting CDK6 using drug repurposing approach, The role of the nucleolus in regulating cell cycle, Chromatin regulators in DNA replication and genome stability maintenance during S-phase, Role of macrophage in cancer cell progression and targeted immunotherapies, and much more.
Donev
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1. Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest
Anupam Bishayee
2. Viral infection on through Cell Cycle Regulation
Selvaraj Chandrabose Sr.
3. Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach
George Priya Doss C
4. Controlling cell proliferation by targeting CDK6 using drug repurposing approach
George Priya Doss C
5. Cdk Regulators: Growth Arrest or Apoptosis? Scenarios in normal and cancerous cells
George Priya Doss C
6. Targeting cell cycle signaling pathways for cancer therapy
Wenyi Wei
7. The role of the nucleolus in regulating cell cycle
Lisa Bouchier-Hayes
8. Chromatin regulators in DNA replication and genome stability maintenance during S-phase
Anastas Gospodinov
9. Role of macrophage in cancer cell progression and targeted immunotherapies
Durba Pal
10. Anti-cancer drug molecules targeting cancer cell cycle and proliferation
Durba Pal
11. Cellular signals integrate cell cycle and metabolic control in cancer
Sarawut Jitrapakdee
12. Therapeutic targeting and proliferation of HSCs by small molecules and biologicals
Fatih Kocabas and Esra Albayrak
13. Mechanism of cell cycle regulation and cell proliferation during human viral infection
Vijay Kumar Prajapati
14. Cyclin-dependent kinases; Role, regulation, and therapeutic targets in cancer
Ajaz A. Bhat
Donev, Rossen
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.
