Cognitive Impairment and Dementia in Parkinson's Disease

1. Auflage 2010
ISBN: 978-0-19-956411-8
Verlag: Oxford University Press

Buch, Englisch, 288 Seiten, Format (B × H): 178 mm x 252 mm, Gewicht: 646 g

Parkinson's disease has long been perceived as a pure motor disorder, partly due to its initial description by James Parkinson, who suggested that "senses and intellect remain intact", and partly due to the fact that patients with PD did not survive long, before effective treatment became available. As the survival time of patients with Parkinson's disease has substantially increased due to modern treatment, it has become apparent that cognitive deficits and dementia are also
frequent features, especially in elderly patients. With the progression of the disease and age, dementia develops in a substantial number of patients and constitutes a major therapeutic challenge. Dementia has thus increasingly been the focus of research and practice in recent years and a large body of
knowledge has been accumulated. Despite these developments there has been no single volume dedicated to this topic.
This book provides an extensive overview of the current status of knowledge pertaining to cognitive impairment and dementia associated with Parkinson's disease, intended as a reference book for general neurologists, neurology residents and also those with a special interest in movement disorders. In this edited volume experts in the field describe in detail all aspects of cognitive impairment and dementia in Parkinson's disease, including epidemiology, spectrum of clinical features, pathology,
neurochemistry and genetics, findings in auxiliary investigations, relation to other neurodegenerative disorders, diagnostic process and management, and rounded up by discussion of future research directions and expectations. The text is complemented and enriched with tables, figures and heavily
referenced to encompass all relevant literature.

Zielgruppe

This book is designed for neurologists, neurology residents, movement disorder specialists, and neuropsychologists, but will also be of interest to psychiatrists, geriatricians, interested general practitioners, neuroscientists, and specialist nurses.

Autoren/Hrsg.

Emre, Murat

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Psychiatrie, Sozialpsychiatrie, Suchttherapie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Geriatrie, Gerontologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pflege Fachpflege

Inhaltsverzeichnis

1: Murat Emre: Introduction
2: Dag Aarsland: The epidemiology of dementia associated with Parkinson's disease
3: Murat Emre: General features, mode of onset and the course of dementia in Parkinson`s disease
4: Kolbjørn Brønnick: Cognitive profile in Parkinson's disease dementia
5: Daniel Weintraub and Eugenia Mamikonyan: Neuropsychiatric symptoms in Parkinson's disease dementia
6: Paolo Barone and Gabriella Santangelo: The interaction between affect and executive functions in Parkinson's disease
7: David J Burn: Motor symptoms and phenotype in patients with Parkinson's disease dementia
8: JM Hausdorff, G Yogev-Seligman, M Plotnik, A Mirelman, N Giladi: Interaction between cognition and gait in patients with Parkinson's disease
9: Eduardo Tolosa and Alex Iranzo: Disorders of sleep and autonomic function in Parkinson's disease dementia
10: Michael J. Firbank & John T O'Brien: Neuroimaging in Parkinsons' Disease Dementia
11: Yasuyuki Okuma and Yoshikuni Mizuno: Electrophysiological and other auxiliary investigations in patients with Parkinson's disease dementia
12: Rita Guerreiro, Andrew Singleton: The genetic basis of dementia in Parkinson's disease
13: Margaret Ann Piggott and Elaine K Perry: Neurochemical pathology of Parkinson's disease dementia
14: Gonzalo J. Revuelta and Carol Lippa: Pathological correlates of dementia in Parkinson's disease
15: Elise Caccappolo and Karen Marder: Cognitive impairment in non-demented patients with Parkinson's disease
16: Clive Ballard, Dag Aarsland: Spectrum of lewy body dementias: relationship of PD-D to DLB
17: Jaime Kulisevsky and Javier Pagonabarraga: Spectrum of disorders with Parkinsonism and dementia
18: Murat Emre: Diagnosis of dementia in Parkinson's disease
19: Ian McKeith and Murat Emre: Management of Parkinson's disease dementia and dementia with lewy bodies
20: John Hardy: Parkinson's disease: what will the future bring?

Über Autor(innen)

Professor Murat Emre was born in 1956 in Eregli, Turkey. After studying medicine at the Istanbul Faculty of Medicine he trained in Neuroscience and Clinical Neurology at the University of Zürich. He then worked in the fields of neurorehabilitation and clinical research in Switzerland for several years. He trained in movement disorders with Prof. David Marsden at the Queen Square National Hospital for Nervous Diseases, London and in behavioral neurology with
Prof. Marsel Mesulam at the Beth Israel Hospital and Harvard Medical School. In 1996 he was appointed as Professor of Neurology at the Istanbul Faculty of Medicine where he started the Behavioral Neurology and Movement Disorders Unit, which he has been chairing since then. His research interests are in
Parkinson's disease and related disorders, in particular cognitive aspects of the disease, Alzheimer's disease and related dementias.