Gaudillière / Rheinberger From Molecular Genetics to Genomics

The Mapping Cultures of Twentieth-Century Genetics
Erscheinungsjahr 2004
ISBN: 978-1-134-33408-7
Verlag: CRC Press
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 244 Seiten

Reihe: Routledge Studies in the History of Science, Technology and Medicine

With the rise of genomics, the life sciences have entered a new era. Maps of genomes have become the icons for a comprehensive knowledge of the organism on a previously unattained level of complexity, and the organisation of genetic knowledge in maps has been a major driving force in the establishment of the discipline. This book provides a comprehensive history of molecular genetics and genomics.

The first section of the book shows how the genetic cartography of classical genetics was linked to the molecular analysis of gene structure through the introduction of new model organisms such as bacteria and through the invention of new experimental tools such as gene transfer. The second section addresses the moral and political economy of human genome sequencing in all its technical, epistemic, social and economic complexity.

With detailed analyses of the scientific practices of mapping and its illustration of the diversity of mapping practices this book is a significant contribution to the history of genetics. A companion volume from the same editors - Classical Genetic Research and Its Legacy: The Mapping Cultures of Twentieth Century Genetics - covers the history of mapping procedures as they were developed in classical genetics.

Autoren/Hrsg.

Gaudillière, Jean-Paul

Rheinberger, Hans-Jörg

Fachgebiete

• Geisteswissenschaften Geschichtswissenschaft Geschichtswissenschaft Allgemein

Inhaltsverzeichnis

Section 1. Molecularizing Maps

1. Angela Creager. Mapping Genes in Microorganisms

2. Frederic L. Holmes. Seymour Benzer and the Convergence of Molecular Biology with Classical Genetics

3. Marcel Weber. Walking on the Chromosome: Drosophila and the Molecularization of Development

4. Scott Gilbert. Gene Expression Maps: The Cartography of Transcription

5. Soraya de Chadarevian. Mapping the Worm's Genome: Tools, Networks, Patronage

Section 2. The Moral and the Political Economy of Human Genome Sequencing

6. Stephen Hilgartner. Making Maps and Making Social Order: Governing American Genome Centers, 1988-93

7. Alain Kaufmann. Mapping the Human Genome at Généthon Laboratory: The French Muscular Dystrophy Association and the Politics of the Gene

8. Adam Bostanci. Sequencing Human Genomes

9. Gísli Pálsson. Decoding Relations and Disease: The Icelandic Biogenetic Project

Über Autor(innen)

Jean-Paul Gaudillière is a senior researcher at the National Institute of Health (INSERM), Paris. His work has addressed many aspects of the history of molecular biology and of the biomedical sciences during the twentieth century. His contemporary research focuses on the history of biological drugs. He is the co-editor of Heredity and Infection: A History of Disease Transmission (2002). Hans-Jörg Rheinberger is Director at the Max Planck Institute for the History of Science in Berlin. He has published numerous papers and books in molecular biology and the history of science, including a co-edited collection, The Concept of the Gene in Development and Evolution (2000).