Clinical Trials in Oncology, Third Edition

3. Auflage 2016
ISBN: 978-1-138-19911-8
Verlag: CRC Press

Buch, Englisch, 264 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 409 g

Reihe: Chapman & Hall/CRC Interdisciplinary Statistics

The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data.

Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.

Zielgruppe

Professional Practice & Development

Autoren/Hrsg.

Green, Stephanie

Benedetti, Jacqueline

Smith, Angela

Crowley, John

Fachgebiete

• Mathematik | Informatik Mathematik Stochastik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Epidemiologie, Medizinische Statistik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung

Inhaltsverzeichnis

1. Introduction, 2. Statistical Concepts, 3. The Design of Clinical Trials, 4. Phase I and Phase I/II Trials, 5. Phase II Trials, 6. Phase III Trials, 7. Data Management and Quality Control, 8. Reporting of Results, 9. Pitfalls, 10. Exploratory Analyses, 11. Summary and Conclusions, References, Index

Über Autor(innen)

Stephanie Green, Jacqueline Benedetti