Grune / Catalgol / Jung Protein Oxidation and Aging

1. Auflage 2012
ISBN: 978-1-118-49301-4
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 516 Seiten, E-Book

Reihe: Wiley Series in Protein and Peptide Science

Reviews our current understanding of the role of proteinoxidation in aging and age-related diseases

Protein oxidation is at the core of the aging process. Settingforth a variety of new methods and approaches, this book helpsresearchers conveniently by exploring the aging process anddeveloping more effective therapies to prevent or treat age-relateddiseases. There have been many studies dedicated to therelationship between protein oxidation and age-related pathology;now it is possible for researchers and readers to learn newtechniques as utilizing protein oxidation products as biomarkersfor aging.

Protein Oxidation and Aging begins with a description ofthe tremendous variety of protein oxidation products. Furthermore,it covers:

* Major aspects of the protein oxidation process

* Cellular mechanisms for managing oxidized proteins

* Role of protein oxidation in aging

* Influence of genetic and environmental factors on proteinoxidation

* Measuring protein oxidation in the aging process

* Protein oxidation in age-related diseases

References at the end of each chapter serve as a gateway to thegrowing body of original research studies and reviews in thefield.

Autoren/Hrsg.

Grune, Tilman

Catalgol, Betul

Jung, Tobias

Uversky, Vladimir

Über Autor(innen)

TILMAN GRUNE, MD, is Full Professor and Director of theInstitute of Nutrition at Friedrich Schiller University Jena. Hisresearch examines the biological phenomenon of oxidative stress. Inparticular, his research group has been investigating the oxidativestress response of cells and organisms and the protective influenceof antioxidants.
BETUL CATALGOL, MD, is Assistant Professor in the Facultyof Medicine and the Department of Biochemistry at MarmaraUniversity. She is coauthor of Proteasome and NeurodegenerativeDiseases, Proteasome and Cancer, and Protein CarbonylMeasurement by Enzyme-Linked Immunosorbent Assay.
TOBIAS JUNG, PhD, is a Research Assistant at FriedrichSchiller University Jena. He is coauthor of Structure of theProteasome.