Hedgehog Signaling

Erscheinungsjahr 2012
ISBN: 978-0-12-394622-5
Verlag: William Andrew Publishing

Buch, Englisch, 584 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 880 g

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on hedgehog signaling.

Zielgruppe

Researchers, faculty, and graduate students interested in cutting-edge review concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested.

Autoren/Hrsg.

Weitere Mitwirkende

Litwack, Gerald

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Endokrinologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Biochemie (med.)
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

- Hedgehog Signaling

Siu Wah Choy, Shuk Han Cheng

- Canonical and Non-Canonical Hedgehog/GLI Signaling in Hematological Malignancies

Fritz Aberger, Daniela Kern, Richard Greil and Tanja Nicole Hartmann

- Non-Canonical Hedgehog Signaling

Donna Brennan, Xiaole Chen, Lan Cheng, My Mahoney, and Natalia A Riobo

- Gli Protein Nuclear Localization Signal

Minoru Hatayama and Jun Aruga

- Mammalian Homologues of Drosophila Fused Kinase

Alla Maloverjan and Marko Piirsoo

- Identification, Functional Characterization and Pathobiological Significance of GLI1 Isoforms in Human Cancers

Richard L. Carpenter, Hui-Wen Lo

- Gli-Similar (Glis) Proteins: Their Mechanisms of Action, Physiological Functions, and Roles in Disease

Kristin Lichti-Kaiser, Gary ZeRuth, Hong Soon Kang, Shivakumar Vasanth, and Anton M. Jetten

- Sonic Hedgehog Regulates Wnt Activity During Neural Circuit Formation

Nicole H. Wilson and Esther T. Stoeckli

- Hedgehog/Gli Control by Ubiquitination/Acetylation Interplay

Alberto Gulino, Lucia Di Marcotullio, Gianluca Canettieri, Enrico Desmaele, Isabella Screpanti

- Palmitoylation of Hedgehog Proteins

John A. Buglino and Marilyn D. Resh

- Phosphorylation Regulation of Hedgehog Signaling

Jianhang Jia

- Protein Kinase A Activity and Hedgehog Signaling Pathway

Tomoya Kotani

- Phosphorylation of Gli by Camp-Dependent Protein Kinase

Yoshinari Asaoka

- ZFP932 Suppresses Cellular Hedgehog Response and Patched1 Transcription

G. Jason Huang, Zhenhua He and Liang Ma

- A New Era for an Ancient Drug; Arsenic Trioxide and Hedgehog Signaling

Elspeth M. Beauchamp and Aykut Üren

- Aberrations and Therapeutics Involving the Developmental Pathway Hedgehog in Pancreatic Cancer

Fergal Crothur Kelleher

- Sonic Hedgehog Signaling and Potential Therapeutic Indications

Nicholas C. Bambakidis, Kaine Onwuzulike

- Sonic Hedgehog on Microparticles and Neovascularization

Raffaella Soleti and Maria Carmen Martinez

- 'Patch'-ing Up the Neurons: Revival or Enervation?

Sayantani Ghosh, Arunabha Chakrabarti and Debashis Mukhopadhyay

- Activation of Hedgehog Pathway in Gastrointestinal Cancers

Ling Yang, Xiulan Su, Jingwu Xie

- The Role Of Sonic Hedgehog as a Regulator of Gastric Function and Differentiation

Rui Feng, Chang Xiao and Yana Zavros

- Sonic Hedgehog-Mediated Synergistic Effects Guiding Angiogenesis and Osteogenesis

Sabine Fuchs, Eva Dohle, Charles James Kirkpatrick

- Hedgehog Inhibition as an Anti-Cancer Strategy

G. Praveen Raju, and Diane Pham

Über Autor(innen)

Litwack, Gerald
Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)