Inhibitors of the Ras Superfamily G-proteins, Part B

Erscheinungsjahr 2014
ISBN: 978-0-12-420146-0
Verlag: William Andrew Publishing

Buch, Englisch, 280 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 570 g

Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss inhibitors of the Ras superfamily G-proteins.

Zielgruppe

Researchers in biochemistry, molecular and cell biology, pharmacology, and cancer

Autoren/Hrsg.

Weitere Mitwirkende

Tamanoi, Fuyuhiko

Der, Channing J.

Fachgebiete

• Naturwissenschaften Biowissenschaften Enzymologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

- Discovery of Small-Molecule Ras Inhibitors that Display Anti-Tumor Activity by Interfering with Ras.GTP-Effector InteractionFumi Shima, Yoko Yoshikawa, Shigeyuki Matsumoto and Tohru Kataoka
- An Orthosteric Inhibitor of the RAS-SOS InteractionSeth Nickerson, Stephen T. Joy, Paramjit S. Arora and Dafna Bar-Sagi
- Conformation-Specific Inhibitors of Raf kinasesXiaolun Wang and Kristin Schleicher
- Inhibitors of the ERK Mitogen-activated Protein Kinase Cascade for Targeting RAS Mutant CancersLeanna Gentry, Ahmed A. Samatar and Channing J. Der
- Inhibiting the RAS - PI3K Pathway in Cancer TherapyClare Sheridan and Julian Downward
- The RalGEF/Ral Pathway: Evaluating an Intervention Opportunity for Ras CancersJonathan M. Cooper, Brian O. Bodemann and Michael A. White
- p21-Activated Kinase InhibitorsJoachim Rudolph, James J. Crawford, Klaus P. Hoeflich, and Jonathan Chernoff
- Recent Progress in Developing Small Molecule Inhibitors Designed to Interfere with Ras Membrane Association: Towards Inhibiting K-Ras and N-Ras Functions Fuyuhiko Tamanoi and Jie Lu
- Synthetic Lethal Genetic Screens in Ras Mutant CancersBing Yu and Ji Luo

Über Autor(innen)

Tamanoi, Fuyuhiko
Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997.