Khan / Ellis / Hanby Precision Molecular Pathology of Breast Cancer

1. Auflage 2015
ISBN: 978-1-4939-2886-6
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 10, 338 Seiten, eBook

Reihe: Molecular Pathology Library

This volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.

Written by experts in the field,

Precision Molecular Pathology of Breast Cancer

is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Khan, Ashraf

Ellis, Ian O.

Hanby, Andrew M.

Cosar, Ediz F.

Rakha, Emad A.

Kandil, Dina

Inhaltsverzeichnis

Molecular basis of breast cancer imaging.- Familial Breast Cancer and Genetic Predisposition in Breast Cancer.- Modelling the Molecular Pathology of Breast Cancer Initiation.- Molecular Pathology of Precancerous Lesions of the Breast.- Breast Cancer Stem Cells: Role in Tumor Initiation, Progression and Targeted Therapy.- Molecular Pathology of Pre-Invasive Ductal Carcinoma. -Molecular Pathology of Lobular Carcinoma

Ali Sakhdari, Lloyd Hutchinson, Ediz Cosar.- Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications.- Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy.- Molecular Classification of Breast Cancer.- Triple Negative Breast Cancer: Subtypes with Clinical Implications.- Molecular-based Diagnostic, Prognostic and Predictive Tests in Breast Cancer.- Role of MicroRNAs in Breast Cancer.- Molecular Pathology of Fibroepithelial Neoplasms of the Breast.- Molecular Features of Mesenchymal Tumors of the Breast.- Molecular Pathology of Breast Cancer Metastasis.- The molecular pathology of chemoresistance during the therapeutic response in breast cancer.- The Molecular Pathology of Male Breast Cancer.- Specimens for Molecular Testing in Breast Cancer.

Über Autor(innen)

Ashraf Khan, MD, FRCPath

University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA

Ian O. Ellis, MD, FRCPath

University of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK

Andrew M. Hanby, BM, FRCPath

St. James University Hospital/University of Leeds, Leeds Institute of Cancer and Pathology, Leeds, West Yorkshire, UK

Ediz F. Cosar, MD

UMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA

Emad Rakha, MD, PhD, FRCPath

University of Nottingham, Department of Histopathology, Nottingham City Hospital, Nottingham, UK

Dina Kandil, MD

UMassMemorial Medical Center, University of Massachusetts Medical School, Department of Pathology, Worcester, MA, USA