Autophagy at the Cell, Tissue and Organismal Level

1. Auflage 2016
ISBN: 978-3-319-33143-0
Verlag: Springer International Publishing

Buch, Englisch, 103 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 1825 g

Reihe: SpringerBriefs in Cell Biology

This book provides an expert summary of autophagy, a relatively new but rapidly expanding field of biomedical science with important implications in health and disease. After a historical review ranging up to the identification of autophagy genes in mammals, the authors discuss the signaling pathways that regulate autophagy, the mechanism of autophagosome formation and the physiological roles of autophagy in development, ageing, neurodegeneration, immune function and cell differentiation. A comprehensive list of useful antibodies for studying autophagy compiled as a community effort is included at the end. The book is intended for newcomers to the field, as well as more experienced researchers looking for a condensed but comprehensive introduction to the physiological function and regulation of the autophagic pathway in mammalian organisms.

Zielgruppe

Research

Autoren/Hrsg.

Ktistakis, Nicholas T.

Karanasios, Eleftherios

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Autophagy (Autophagia) from 1860 to 1963.- History of Autophagy after 1963.- Signalling in Autophagy.- Autophagosome Formation.- Physiological Role of Autophagy and Implications in Disease.- Studying autophagy: List of useful antibodies produced via a community effort.