Li / Lin Photofunctional Nanomaterials for Biomedical Applications

1. Auflage 2024
ISBN: 978-3-527-84532-3
Verlag: Wiley-VCH
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 588 Seiten, E-Book

highlights the controlled synthesis of photofunctional nanoparticles and their hybrid nanocomposites as well as their full potential in biomedical applications.

Autoren/Hrsg.

Li, Chunxia

Lin, Jun

Inhaltsverzeichnis

Foreword

Preface

 

1 GENERAL INTRODUCTION AND BACKGROUND OF PHOTOFUNCTIONAL NANOMATERIALS IN BIOMEDICAL APPLICATIONS

1.1 Introduction to Nanomaterials

1.2 Introduction and Classification of Photofunctional Nanomaterials

1.3 Introduction to Nanobiomedicine

1.4 Classification of Photofunctional Nanomaterials

1.5 Conclusion

 

2 MECHANISM IN RARE-EARTH-DOPED LUMINESCENCE NANOMATERIALS

2.1 Introduction

2.2 Composition of RE-Doped Luminescence Nanomaterials: Substrate (Host), Activator, and Sensitizer

2.3 Mechanism of RE-Doped Luminescence Nanomaterials

2.4 Luminescence Modulation

 

3 UPCONVERSION AND NIR-II LUMINESCENCE MODULATION OF RARE-EARTH COMPOSITES USING MATERIAL INFORMATICS

3.1 Introduction

3.2 Typical Processes of Upconversion Luminescence

3.3 Synthesis Methods of Upconversion Nanoparticles

3.4 Material Informatics in UCL

3.5 Cancer Therapy Based on UCNPs

3.6 Conclusion and Perspective

 

4 COMPOSITES BASED ON LANTHANIDE-DOPED UPCONVERSION NANOMATERIALS AND METAL-ORGANIC FRAMEWORKS: FABRICATION AND BIOAPPLICATIONS

4.1 Introduction

4.2 Fabrications of Composites

4.3 Bioapplications

4.4 Conclusion and Perspectives

 

5 LANTHANIDE-DOPED NANOMATERIALS FOR LUMINESCENCE BIOSENSING AND BIODETECTION

5.1 Introduction

5.2 Basics of Optical Bioprobe and Lanthanide-Doped Nanoparticles

5.3 Synthesis and Functionalization of Lanthanide-Dope Nanocrystals

5.4 Applications of Luminescence Biosensing and Biodetection

5.5 Integrated Devices for Point-of-Care Testing

5.6 Summary

 

6 RARE EARTH LUMINESCENT NANOMATERIALS FOR GENE DELIVERY

6.1 Introduction

6.2 UCNPs Nanovectors

6.3 Surface Modification

6.4 Increasing Endosomal Escape

6.5 Controlling Delivery Strategy

6.6 Gene Therapy and Syndication

6.7 Other Lanthanide-Based Nanovectors

6.8 Perspective

 

7 BIOSAFETY OF RARE-EARTH-DOPED NANOMATERIALS

7.1 Internalization of UCNPs into Cells

7.2 Distribution of UCNPs

7.3 Excretion Behavior of UCNPs

7.4 The Toxic Effect of Cell Incubated with UCNPs

7.5 Toxic Effect of UCNPs In Vivo

7.6 Conclusions and Prospects

 

8 DESIGN AND CONSTRUCTION OF PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY OF TUMOR

8.1 Introduction

8.2 Small Molecule Photosensitizers

8.3 Metal Complexes

8.4 Inorganic Photosensitizers

8.5 Conclusions and Perspectives

 

9 PERSISTENT LUMINESCENT MATERIALS FOR OPTICAL INFORMATION STORAGE APPLICATIONS

9.1 Introduction

9.2 Luminescent Mechanism of Persistent Luminescent Materials with Deep Traps

9.3 Persistent Luminescent Materials with Deep Traps

9.4 Outlooks

 

10 THE APPLICATION OF TERNARY QUANTUM DOTS IN TUMOR-RELATED MARKER DETECTION, IMAGING, AND THERAPY

10.1 Introduction

10.2 Conclusion

 

11 NANOMATERIALS-INDUCED PYROPTOSIS AND IMMUNOTHERAPY

11.1 Discovery and Definition of Pyroptosis

11.2 Mechanisms of Pyroptosis

11.3 Pyroptosis and Tumor Immunotherapy

11.4 Summary and Outlook

 

12 NIR LIGHT-ACTIVATED CONVERSION NANOMATERIALS FOR PHOTOTHERMAL/IMMUNOTHERAPY

12.1 Introduction

12.2 The Photothermal Conversion Mechanism

12.3 Classification of Inorganic Photothermal Materials

12.4 Mechanisms of PTT and Immunotherapy

12.5 Nanomaterial-Based Photothermal/Immunotherapy

12.6 Summary and Outlook

 

13 NEAR-INFRARED REGION-RESPONSIVE ANTIMICROBIAL NANOMATERIALS FOR THE TREATMENT OF MULTIDRUG-RESISTANT BACTERIA

13.1 Introduction

13.2 The Antibacterial Mechanisms of Photofunctional Antibacterial Nanomaterials

13.3 Photofunctional Nanomaterials and Antibacterial Activity Against MDR Bacteria

13.4 Limitations and Challenges

13.5 Conclusions

 

14 PHOTOELECTROCHEMICAL NANOMATERIALS FOR BIOSENSING APPLICATIONS

14.1 Introduction

14.2 Classification of Photoelectrochemical Materials

14.3 Introduction to Biorecognition Elements

14.4 Factors Affecting the Photocurrent Signal

14.5 Signal Amplification and Bursting Strategies

14.6 Applications of Photoelectrochemical Biosensors

14.7 Challenges and Potential Clinical Applications

 

15 X-RAY-INDUCED PHOTODYNAMIC THERAPY FOR DEEP-SEATED TUMORS

15.1 Introduction

15.2 Mechanisms of Interaction Between X-Rays and Scintillat

Über Autor(innen)

Chunxia Li is a Professor at Shandong University. Her research interests include the controllable synthesis of multifunctional nanomaterials and their bioapplication.

 

Jun Lin is a Professor at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. His research interests include bulk and nanostructured luminescent materials and multifunctional composite materials, together with their applications in the display, lighting, and biomedical fields.