Biostatistical Methods

2002
ISBN: 978-0-89603-951-3
Verlag: Humana Press

Buch, Englisch, Band 184, 216 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 554 g

Reihe: Methods in Molecular Biology

Leading biostatisticians and biomedical researchers describe many of the key techniques used to solve commonly occurring data analytic problems in molecular biology, and demonstrate how these methods can be used in the development of new markers for exposure to a risk factor or for disease outcomes. Major areas of application include microarray analysis, proteomic studies, image quantitation, genetic susceptibility and association, evaluation of new biomarkers, and power analysis and sample size.

Zielgruppe

Research

Autoren/Hrsg.

Looney, Stephen W.

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

Statistical Contributions to Molecular Biology.- Linking Image Quantitation and Data Analysis.- to Microarray Experimentation and Analysis.- Statistical Methods for Proteomics.- Statistical Methods for Assessing Biomarkers.- Power and Sample Size Considerations in Molecular Biology.- Models for Determining Genetic Susceptibility and Predicting Outcome.- Multiple Tests for Genetic Effects in Association Studies.- Statistical Considerations in Assessing Molecular Markers for Cancer Prognosis and Treatment Efficacy.- Power of the Rank Test for Multi-Strata Case-Control Studies with Ordinal Exposure Variables.