Metalloproteins and Motor Proteins

Erscheinungsjahr 2024
ISBN: 978-0-443-19344-6
Verlag: Elsevier Science & Technology

Buch, Englisch, Format (B × H): 152 mm x 229 mm, Gewicht: 1220 g

Metalloproteins and Motor Proteins, Volume 141 focuses on recent advances in studying metalloproteins and motor proteins, along with their roles in different pathologies and drug-resistance. Chapters include Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii, The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes, Role of Metal ion in ion channel Mechanisms, A model of microtubule depolymerization by kinesin-8 motor proteins, Metalloproteins and metalloproteomics in health and disease, Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders, and much more.

Additional chapters cover Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy, Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer, Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis, Role of transmembrane proteins in metalloproteins and motor proteins in human aging, Vesicle transport of metalloproteinases, Motor proteins and spermatogenesis, and much more.

Autoren/Hrsg.

Weitere Mitwirkende

Donev, Rossen

Fachgebiete

• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii
George Priya Doss C, Hatem Zayed, Santhosh ME, Prasanna Kumar Selvam, Mohanraj Gopikrishnan, Karthick Vasudevan, Mangesh R and Charles Emmanuel Jebaraj W
2. The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes
Kshatresh Dutta Dubey and Ankita Tripathi
3. Role of Metal ion in ion channel Mechanisms
Selvaraj Chandrabose Sr.
4. A model of microtubule depolymerization by kinesin-8 motor proteins
Ping Xie
5. Metalloproteins and metalloproteomics in health and disease
Iman Hassan Ibrahim
6. Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders
George Priya Doss C and Hatem Zayed
7. Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy
George Priya Doss C, Mangesh R, Hatem Zayed, Karthick Vasudevan, Madhana Priya N, Sidharth Kumar N, Udhaya Kumar S and Mohanraj G
8. Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer
Rolland Reinbold
9. Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis
Rolland Reinbold
10. Role of transmembrane proteins in metalloproteins and motor proteins in human aging
Rolland Reinbold
11. Vesicle transport of metalloproteinases
Yoshifumi Itoh
12. Motor proteins and spermatogenesis
C. Yan Cheng
13. Motor proteins regulates Tauopathy in Neurodegeneration/AD
Subashchandrabose Chinnathambi
14. The crosstalk between ECM proteins and Tau
Subashchandrabose Chinnathambi
15. Microbial Metalloproteins and its role in xenobiotic degradation and ROS scavenging
Krishna Kant Sharma
16. Exploring metalloproteins found in the secretion of venomous species: biological role and therapeutic application
Cícero Alves Lopes Júnior, Mikael Kélvin de Albuquerque Mendes, Michely da Silva Sousa, Edivan Carvalho Vieira, Tatianny de Araujo Andrade and Jemmyson Romário de Jesus
17. Studying Metalloproteins by Single-molecule Force Spectroscopy
Peng Zheng
18. Coordination, cooperation, competition, crowding and congestion of molecular motors: Theoretical models and computer simulations
Ambarish Kunwar
19. Epigenetic dysregulation in cancers by Isocitrate dehydrogenase 2 (IDH2)
Anuraj Nayarisseri Sr.

Über Autor(innen)

Donev, Rossen
Rossen Donev received his PhD degree in 1999 from the Institute of Molecular Biology, Bulgarian Academy of Sciences. He did postdoctoral training at Imperial Cancer Research Fund, UK (renamed after the merger with Cancer Research Campaign to Cancer Research UK, London Research Institute) and Cardiff University. In 2007 he was awarded a New Investigator Grant Award from the Medical Research Council (UK) to establish himself as an independent Principle Investigator. In 2010 Dr. Donev was appointed Senior Lecturer at Swansea University. In 2016 Dr. Donev joined MicroPharm Ltd (UK) where currently he is Head of Research. He has published more than 60 research papers, chaired scientific meetings and given invited plenary talks. Rossen Donev has consulted on projects related to development of treatments for neurodevelopmental disorders and cancer therapies. He serves as Editor-in-Chief of the Advances in Protein Chemistry and Structural Biology and on editorial board of several other journals. His research interests include signaling pathways involved in neuropsychiatric disorders and tumor escape from the immune system, and development of therapeutic strategies for their treatment. More recently he has focused on development of immunotherapeutics for non-systemic applications.