Molecular Biology of RGS Proteins

Erscheinungsjahr 2009
ISBN: 978-0-12-374759-4
Verlag: William Andrew Publishing

Buch, Englisch, 384 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 650 g

Molecular Biology of RGS Proteins, a volume of Progress in Molecular Biology and Translational Science, will include historical discussion of RGS proteins, the role of RGS proteins in addiction, depression and Parkinson's disease and the biology and functional regulation of RGS9 isoforms. This publication further discusses RGS proteins in cellular signaling, protein control in lymphocyte function, and alternative splicing of RGS transcripts and nuclear RGS proteins, offering the latest in research of RGS proteins.

Zielgruppe

Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine will value this volume of Progress in Molecular Biology and Translational Science.

Autoren/Hrsg.

Weitere Mitwirkende

Fisher, Rory A.

Fachgebiete

• Mathematik | Informatik EDV | Informatik Angewandte Informatik Bioinformatik
• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Angewandte Biologie Bioinformatik

Inhaltsverzeichnis

1. RGS proteins: the early days
Henrik Dohlman

2. The role of RGS proteins in addiction, depression and Parkinsons disease
Vanna Zachariou

3. Biology and functional regulation of RGS9 isoforms
Kirill Martemyanov

4. RGS protein function in C. elegans
Michael Koelle

5.G Beta 5 in the visual system
Jason Chen

6. Roles of RGS proteins and RGS homology domains in signaling
John Tesmer

7.Gb5-RGS protein complexes
Vladlen Slepak

8. Multifunctional roles of RGS Proteins in cellular signaling
John Hepler

9. RGS protein control of lymphocyte function
John Kehrl

10. RGS-insensitive G proteins to study endogenous RGS protein function
Richard Neubig

11. Alternative splicing of RGS transcripts and nuclear RGS proteins
Rory Fisher

Über Autor(innen)

Fisher, Rory A.
Dr. Fisher is a 1983 graduate of Iowa State University (Ph.D.), who performed post-doctoral research at the University of Texas Health Science Center, San Antonio, before joining the faculty in Pharmacology at the University of Iowa in 1987. He was promoted to associate professor in 1993 and to professor in 2004. He has a secondary appointment in the Department of Internal Medicine and is a member of the Molecular and Cellular Biology interdisciplinary graduate program, the Holden Cancer Center, the Medical Scientist Training Program, and the Gene Therapy Center. His research focuses on the biology and signaling of RGS proteins and G proteins. He has served on numerous NIH study sections and his funding includes an R01 to study novel actions of RGS6 in tumor suppression and DNA damage signaling.